Identification of the Structural Determinants for Anticancer Activity of a Ruthenium Arene Peptide Conjugate

Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

(2013) Wolfgang Kandioller et al.   CHEMICAL COMMUNICATIONS

Probing the Interaction of Cisplatin with Cytochrome c by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2012) Ningbo Zhang et al.   ANALYTICAL CHEMISTRY

Peptide–Drug Conjugate Linked via a Disulfide Bond for Kidney Targeted Drug Delivery

(2012) Qian Geng et al.   BIOCONJUGATE CHEMISTRY

Effects of Enzymatic Activation on the Distribution of Fluorescently Tagged MMP-2 Cleavable Peptides in Cancer Cells and Spheroids

(2012) Natsuho Yamamoto et al.   BIOCONJUGATE CHEMISTRY

Somatostatin Subtype-2 Receptor-Targeted Metal-Based Anticancer Complexes

(2012) Flavia Barragán et al.   BIOCONJUGATE CHEMISTRY

The potential of organometallic complexes in medicinal chemistry

(2012) Gilles Gasser et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Solid-phase synthesis of oxaliplatin–TAT peptide bioconjugates

(2012) Sergey Abramkin et al.   DALTON TRANSACTIONS

Cell-penetrating peptides: classes, origin, and current landscape

(2012) Francesca Milletti   DRUG DISCOVERY TODAY

Arene ruthenium complexes with phosphinoferrocene amino acid conjugates: Synthesis, characterization and cytotoxicity

(2012) Jiří Tauchman et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

The Chemoselective Reactions of Tyrosine-Containing G-Protein-Coupled Receptor Peptides with [Cp*Rh(H2O)3](OTf)2, Including 2D NMR Structures and the Biological Consequences

(2012) H. Bauke Albada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and in vitro cytotoxicity of cis,cis,trans-diamminedichloridodisuccinatoplatinum(iv)–peptide bioconjugates

(2012) Luca Gaviglio et al.   Metallomics

Heterodinuclear Arene Ruthenium Complexes Containing a Glycine-Derived Phosphinoferrocene Carboxamide: Synthesis, Molecular Structure, Electrochemistry, and Catalytic Oxidation Activity in Aqueous Media

(2012) Jiří Tauchman et al.   ORGANOMETALLICS

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

(2012) Christian G. Hartinger et al.   ORGANOMETALLICS

Semi-synthesis of bioactive fluorescent analogues of the cytotoxic marine alkaloid discorhabdin C

(2012) Cary F.C. Lam et al.   TETRAHEDRON

A spontaneous gold(i)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line

(2012) S. David Köster et al.   Chemical Science

Fragmentation methods on the balance: unambiguous top–down mass spectrometric characterization of oxaliplatin–ubiquitin binding sites

(2011) Samuel M. Meier et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Functionalization of Osmium Arene Anticancer Complexes with (Poly)arginine: Effect on Cellular Uptake, Internalization, and Cytotoxicity

(2011) Sabine H. van Rijt et al.   BIOCONJUGATE CHEMISTRY

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins

(2011) Samuel M. Meier et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Influence of the Arene Ligand and the Leaving Group on the Anticancer Activity of (Thio)maltol Ruthenium(II)?(η6-Arene) Complexes

(2010) Muhammad Hanif et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Protease-Activatable Organometal−Peptide Bioconjugates with Enhanced Cytotoxicity on Cancer Cells

(2010) Katrin Splith et al.   BIOCONJUGATE CHEMISTRY

Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS)

(2010) Jonathan P. Williams et al.   CHEMICAL COMMUNICATIONS

Synthesis and cytotoxicity of a bimetallic ruthenocene dicobalt-hexacarbonyl alkyne peptide bioconjugate

(2010) Annika Gross et al.   DALTON TRANSACTIONS

Is the Reactivity of M(II)−Arene Complexes of 3-Hydroxy-2(1H)-pyridones to Biomolecules the Anticancer Activity Determining Parameter?

(2010) Muhammad Hanif et al.   INORGANIC CHEMISTRY

Mannich products of kojic acid and N-heterocycles and their Ru(II)–arene complexes: Synthesis, characterization and stability

(2010) Johanna H. Kasser et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Pyrone derivatives and metals: From natural products to metal-based drugs

(2010) Wolfgang Kandioller et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Shape changes induced by N-terminal platination of ubiquitin by cisplatin

(2010) Jonathan P. Williams et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Modification with Organometallic Compounds Improves Crossing of the Blood-Brain Barrier of [Leu5]-Enkephalin Derivatives in an In Vitro Model System

(2009) Antonio Pinto et al.   CHEMBIOCHEM

Maltol-Derived Ruthenium-Cymene Complexes with Tumor Inhibiting Properties: The Impact of Ligand-Metal Bond Stability on Anticancer Activity In Vitro

(2009) Wolfgang Kandioller et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal chelating systems synthesized using the copper(i) catalyzed azide-alkynecycloaddition

(2009) Harriet Struthers et al.   DALTON TRANSACTIONS

Exploring metallodrug–protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound

(2009) Angela Casini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Transferring the Concept of Multinuclearity to Ruthenium Complexes for Improvement of Anticancer Activity

(2009) Maria G. Mendoza-Ferri et al.   JOURNAL OF MEDICINAL CHEMISTRY

From Pyrone to Thiopyrone Ligands−Rendering Maltol-Derived Ruthenium(II)−Arene Complexes That Are Anticancer Active in Vitro

(2009) Wolfgang Kandioller et al.   ORGANOMETALLICS

Cymantrene conjugation modulates the intracellular distribution and induces high cytotoxicity of a cell-penetrating peptide

(2008) Ines Neundorf et al.   CHEMICAL COMMUNICATIONS

Mitochondria-Penetrating Peptides

(2008) Kristin L. Horton et al.   CHEMISTRY & BIOLOGY

“Click‐to‐Chelate”: Design and Incorporation of Triazole‐Containing Metal‐Chelating Systems into Biomolecules of Diagnostic and Therapeutic Interest

(2008) Harriet Struthers et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent developments on 3-hydroxy-4-pyridinones with respect to their clinical applications

(2008) M. Amélia Santos   COORDINATION CHEMISTRY REVIEWS

Mercury CSD 2.0– new features for the visualization and investigation of crystal structures

(2008) Clare F. Macrae et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: New insights from X-ray diffraction and mass spectrometry studies

(2008) Angela Casini et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety

(2008) Wolfgang Kandioller et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Microwave-assisted solid-phase synthesis, cellular uptake, and cytotoxicity studies of cymantrene–peptide bioconjugates

(2008) Harmel W. Peindy N’Dongo et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

The synthesis, structural characterization and in vitro anti-cancer activity of novel N-(3-ferrocenyl-2-naphthoyl) dipeptide ethyl esters and novel N-(6-ferrocenyl-2-naphthoyl) dipeptide ethyl esters

(2008) Áine Mooney et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Electron capture and transfer dissociation: Peptide structure analysis at different ion internal energy levels

(2008) Hisham Ben Hamidane et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Spectroscopic and Electrochemical Studies of Ferrocenyl Triazole Amino Acid and Peptide Bioconjugates Synthesized by Click Chemistry

(2008) S. David Köster et al.   ORGANOMETALLICS

Synthesis and cytotoxicity of a cobaltcarbonyl–alkyne enkephalin bioconjugate

(2007) Merja A. Neukamm et al.   CHEMICAL COMMUNICATIONS