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Recent Progress in the Application of Atomic Force Microscopy for Supported Lipid Bilayers

Journal

CHEMISTRY-A EUROPEAN JOURNAL
Volume 18, Issue 14, Pages 4148-4155

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201102831

Keywords

membranes; membrane proteins; nanomechanics; scanning probe microscopy; submolecular imaging

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In the past two decades, atomic force microscopy has been widely used for studying supported lipid bilayer related research, including the structure and dynamics of membranes and membrane proteins, and the interaction of membranes with chemical and biological molecules. The focus of this minireview is on the recent progress in the application of atomic force microscopy for supported lipid bilayers. Such progress mainly includes the application in the following aspects: submolecular-resolution imaging, in situ observation, and nanomechanics measurement.

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