Current Chemical Biology Tools for Studying Protein Phosphorylation and Dephosphorylation

A Fluorescent Reporter of the Phosphorylation Status of the Substrate Protein STAT3

(2011) Vanessa K. Lacey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe

(2011) Haibin Shi et al.   CHEMICAL COMMUNICATIONS

A self-immobilizing and fluorogenic unnatural amino acid that mimics phosphotyrosine

(2011) Jingyan Ge et al.   CHEMICAL COMMUNICATIONS

Luminescent Kinase Activity Biosensors Based on a Versatile Bimolecular Switch

(2011) Katie J. Herbst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

(2011) Mingyu Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical genetic strategy for targeting protein kinases based on covalent complementarity

(2011) A. L. Garske et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding the Genetic Code of Escherichia coli with Phosphoserine

(2011) H.-S. Park et al.   SCIENCE

Design and application of genetically encoded biosensors

(2011) Amy E. Palmer et al.   TRENDS IN BIOTECHNOLOGY

A p38α-Selective Chemosensor for use in Unfractionated Cell Lysates

(2010) Cliff I. Stains et al.   ACS Chemical Biology

Phosphorylation-Dependent Kinase-Substrate Cross-Linking

(2010) Sujit Suwal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14-3-3 Proteins

(2010) Hao Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activity-based high-throughput determination of PTPs substrate specificity using a phosphopeptide microarray

(2010) Liqian Gao et al.   BIOPOLYMERS

An unnatural amino acid that mimics phosphotyrosine

(2010) Jingyan Ge et al.   CHEMICAL COMMUNICATIONS

Photocontrol of STAT6 dimerization and translocation

(2010) Sunanda Lahiri et al.   Molecular BioSystems

Next Generation Chemical Proteomic Tools for Rapid Enzyme Profiling

(2009) Mahesh Uttamchandani et al.   ACCOUNTS OF CHEMICAL RESEARCH

Monitoring Protein Kinases in Cellular Media with Highly Selective Chimeric Reporters

(2009) Elvedin Luković et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Chemical Biology of Protein Phosphorylation

(2009) Mary Katherine Tarrant et al.   Annual Review of Biochemistry

Synthesis and peptide incorporation of an unnatural amino acid containing activity-based probe for protein tyrosine phosphatases

(2009) Kui Shen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Photogenerated Quinone Methides as Protein Affinity Labeling Reagents

(2009) Jiangsong Jiang et al.   CHEMBIOCHEM

Small molecule probes that target Ablkinase

(2009) Karunakaran A. Kalesh et al.   CHEMICAL COMMUNICATIONS

Peptide-based activity-based probes (ABPs) for target-specific profiling of proteintyrosine phosphatases (PTPs)

(2009) Karunakaran A. Kalesh et al.   CHEMICAL COMMUNICATIONS

Genetically encoded FRET-based biosensors for multiparameter fluorescence imaging

(2009) Haley J Carlson et al.   CURRENT OPINION IN BIOTECHNOLOGY

Designs and applications of fluorescent protein-based biosensors

(2009) Andreas Ibraheem et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Dynamic visualization of signal transduction in living cells: From second messengers to kinases

(2009) Katie J. Herbst et al.   IUBMB LIFE

Peptide Microarray for High-Throughput Determination of Phosphatase Specificity and Biology

(2008) Hongyan Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid Affinity-Based Fingerprinting of 14-3-3 Isoforms Using a Combinatorial Peptide Microarray

(2008) Candy H. S. Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of SerotoninN-Acetyltransferase Regulation in Vitro and in Live Cells Using Protein Semisynthesis†

(2008) Lawrence M. Szewczuk et al.   BIOCHEMISTRY

Protein kinase substrate identification on functional protein arrays

(2008) Lihao Meng et al.   BMC BIOTECHNOLOGY

Activity-Based Protein Profiling: New Developments and Directions in Functional Proteomics

(2008) Mahesh Uttamchandani et al.   CHEMBIOCHEM

An Improved Mechanism-Based Cross-Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome

(2008) Kai Liu et al.   CHEMBIOCHEM

High-throughput screening of catalytically inactive mutants of protein tyrosine phosphatases (PTPs) in a phosphopeptide microarray

(2008) Hongyan Sun et al.   CHEMICAL COMMUNICATIONS

Peptide Microarrays: Next Generation Biochips for Detection, Diagnostics and High-Throughput Screening

(2008) Mahesh Uttamchandani et al.   CURRENT PHARMACEUTICAL DESIGN

Recognition-Domain Focused Chemosensors: Versatile and Efficient Reporters of Protein Kinase Activity

(2008) Elvedin Luković et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tuning a Three-Component Reaction For Trapping Kinase Substrate Complexes

(2008) Alexander V. Statsuk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryl Vinyl Sulfonates and Sulfones as Active Site-Directed and Mechanism-Based Probes for Protein Tyrosine Phosphatases

(2008) Sijiu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis of Protein Kinase Autophosphorylation Using Expressed Protein Ligation and Computational Modeling

(2008) Kerry A. Pickin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatiotemporal Analysis of Differential Akt Regulation in Plasma Membrane Microdomains

(2008) Xinxin Gao et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Imaging of Phosphorylation Events for Drug Development

(2008) C. T. Chan et al.   MOLECULAR IMAGING AND BIOLOGY

Peptide microarrays for high-throughput studies of Ser/Thr phosphatases

(2008) Hongyan Sun et al.   Nature Protocols