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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

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Complexity and simplicity in the biosynthesis of enediyne natural products

(2010) Zhao-Xun Liang   NATURAL PRODUCT REPORTS

Mitomycins syntheses: a recent update

(2009) Jean-Christophe Andrez   Beilstein Journal of Organic Chemistry

Catalytic Mechanism of BleomycinN-Acetyltransferase Proposed on the Basis of Its Crystal Structure

(2009) Kosuke Oda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fundamental Relationships between Structure, Reactivity, and Biological Activity for the Duocarmycins and CC-1065

(2009) Karen S. MacMillan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Defining the Mode of Action of Tetramic Acid Antibacterials Derived from Pseudomonas aeruginosa Quorum Sensing Signals

(2009) Colin A. Lowery et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quinone methide chemistry of prekinamycins: 13C- labeling, spectral global fitting and in vitro studies

(2009) Omar Khdour et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and Biological Activity of Largazole and Derivatives

(2008) Tobias Seiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A

(2008) Simon J. Crabb et al.   BIOCHEMICAL PHARMACOLOGY

Accurate mass analysis ofN-acyl-homoserine-lactones and cognate lactone-opened compounds in bacterial isolates ofPseudomonas aeruginosaPAO1 by LC-ESI-LTQ-FTICR-MS

(2008) Tommaso R. I. Cataldi et al.   JOURNAL OF MASS SPECTROMETRY

Total Synthesis and Molecular Target of Largazole, a Histone Deacetylase Inhibitor

(2008) Yongcheng Ying et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis and Biological Mode of Action of Largazole: A Potent Class I Histone Deacetylase Inhibitor

(2008) Albert Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine CyanobacteriumSymplocasp.

(2008) Kanchan Taori et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY

Kinamycin-mediated DNA cleavage under biomimetic conditions

(2008) T. Eric Ballard et al.   TETRAHEDRON LETTERS

Possible chemical mechanisms underlying the antitumor activity of S-deoxyleinamycin

(2007) Santhosh Sivaramakrishnan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS