Article
Biochemistry & Molecular Biology
Shipeng Li, Ye Chen, Ying Duan, Yinhui Zhao, Di Zhang, Liyan Zang, Huiyuan Ya
Summary: Research on shoots and roots of Salsola collina Pall revealed significant differences in metabolites, with higher levels of major differential metabolites found in L-Sc. Additionally, major differential secondary metabolites were also found to be at higher levels in L-Sc.
Article
Chemistry, Applied
Wen-Zhi Wang, Zhao-Chun Zhan, Qing Tang, Ming Yan, Neng-Hua Chen, Hai-Yue Zhao, Hao-Yue Zhu, Huan-Qing Zhang, Zhong-Nan Wu, Hao-Yun Wang, Yu-Bo Zhang, Guo-Cai Wang, Yao-Lan Li
Summary: Three new compounds, along with seven known compounds, were isolated from the whole plant of Salsola collina Pall. Their structures and configurations were determined through extensive spectroscopic analysis. One of the compounds exhibited significant anti-inflammatory activity.
NATURAL PRODUCT RESEARCH
(2023)
Article
Food Science & Technology
Kunli Wang, Mo Li, Qianyun Han, Rao Fu, Yuanying Ni
Summary: The study found that the insoluble dietary fiber (IDF) and soluble dietary fiber (SDF) from kiwifruit have different inhibitory effects on alpha-amylase, with IDF showing a stronger inhibition effect. IDF and SDF may attenuate starch hydrolysis through different mechanisms, indicating potential applications in the food and nutraceutical industries.
Review
Chemistry, Medicinal
Yan-Yan Ding, Han Zhou, Bao-Qi Peng-Deng, Bao-Qi Zhang, Zhi-Jun Zhang, Guang-Han Wang, Shao-Yong Zhang, Zheng-Rong Wu, Yi-Rong Wang, Ying-Qian Liu
Summary: Since the isolation of the first natural carbazole alkaloid, murrayanine, from Mwraya Spreng, carbazole alkaloid derivatives have attracted wide attention for their anti-tumor, anti-viral, and anti-bacterial activities. Recent research has shown that carbazole alkaloids and their derivatives exhibit diverse biological activities. This study provides the first comprehensive description of the antifungal and antibacterial activities of carbazole alkaloids in the past decade (2012-2022), including both natural and partially synthesized compounds. The challenges and problems faced by this class of alkaloids are also summarized. This paper will facilitate further exploration of carbazole alkaloids.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Ninon G. E. R. Etsassala, Jelili A. Badmus, Jeanine L. Marnewick, Samuel Egieyeh, Emmanuel. I. Iwuoha, Felix Nchu, Ahmed A. Hussein
Summary: This study found that compounds in the methanolic extract of Plectranthus ecklonii have moderate inhibitory activity against alpha-glucosidase and alpha-amylase, as well as strong antioxidant capacities. This provides potential candidate compounds for the development of antidiabetic drugs.
Article
Biotechnology & Applied Microbiology
Mariana C. L. Aguieiras, Larissa M. Resende, Thayna A. M. Souza, Celso S. Nagano, Renata P. Chaves, Gabriel B. Taveira, Andre O. Carvalho, Rosana Rodrigues, Valdirene M. Gomes, Erica O. Mello
Summary: This study identified a novel AMP (CcDef3) from Capsicum chinense fruits with strong antifungal activity, particularly against Candida species, and demonstrated good inhibitory effects on alpha-amylase activity. AMPs show promise as a potential alternative to combat multidrug resistant pathogens.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2021)
Article
Biochemistry & Molecular Biology
Romeo Toko Feunaing, Alfred Ngenge Tamfu, Abel Joel Yaya Gbaweng, Larissa Mekontso Magnibou, Fidele Ntchapda, Celine Henoumont, Sophie Laurent, Emmanuel Talla, Rodica Mihaela Dinica
Summary: Diabetes mellitus is a metabolic disorder that can cause various health complications, such as kidney failure, blindness, limb amputation, heart attack, and stroke. A study found that compounds extracted from the roots of Pterocarpus erinaceus have the potential to lower blood glucose levels by inhibiting certain enzymes related to carbohydrate digestion.
Article
Food Science & Technology
Kian Aun Chang, Sing Ling Ley, Mei Yan Lee, Hui Yee Yaw, Sook Wai Lee, Lye Yee Chew, Yun Ping Neo, Kin Weng Kong
Summary: The study revealed that Sechium edule shoot is a good source of calcium and iron, with water extraction yielding the highest total phenolic content, methanol extraction yielding the highest total flavonoid and beta-carotene content, and hexane extract showing the best antioxidant performance. Methanol and steaming were identified as the best extraction solvent and cooking method for their efficient extraction and retention of bioactive compounds.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Jia Chen, Yiyuan Tang, Hongjuan Zhou, Jianhua Shao, Wei Ji, Mengya Yang, Chunchao Zhao
Summary: Ten previously undescribed iridoid constituents and one known analogue were isolated from Viburnum chinshanense branches. The structures of all compounds were determined using NMR data and spectroscopic analysis. Compounds 4, 5, and 10 showed significant inhibition against two enzymes.
Article
Biochemistry & Molecular Biology
Jia Chen, Yiyuan Tang, Hongjuan Zhou, Jianhua Shao, Wei Ji, Zihan Wang, Dong Liang, Chunchao Zhao
Summary: Eleven previously undescribed lignan constituents were isolated from the fruits of Viburnum urceolatum. Viburnurcoside J exhibited potent inhibitory activity against alpha-amylase and alpha-glucosidase.
Article
Chemistry, Medicinal
Leyla Guven, Adem Erturk, Fatma Demirkaya Miloglu, Saleh Alwasel, Ilhami Gulcin
Summary: In this study, we evaluated the in vitro antiglaucoma, antidiabetic, anti-Alzheimer's disease, and antioxidant activities of the methanolic and water extracts of Astragalus alopecurus. The extracts showed inhibition ability on various enzymes and exhibited antioxidant properties. These findings provide a foundation for further exploring the therapeutic potential of Astragalus species.
Article
Chemistry, Applied
C. F. De Schepper, P. Michiels, C. Buve, A. M. Van Loey, C. M. Courtin
Summary: The study investigated the activity and inactivation kinetics of α-amylase and β-amylase during barley malt mashing, finding that temperature had an impact on the activity differences among different varieties, but these differences were not reflected in the resulting wort composition after mashing in the actual process.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Sandrine Mewaba Goulefack, Emmanuel Nguefa Happi, Willifred Dongmo Tekapi Tsopgni, Brice Maxime Nangmou Nkouayeb, Stevine Claudiale Popwo Tameye, Anatole Guy Blaise Azebaze
Summary: The chemical investigation of Coffea canephora led to the isolation and structure elucidation of seventeen known compounds. Some of the isolated compounds showed moderate antibacterial and antifungal activities. The research provides valuable insights into the chemical composition and potential pharmacological effects of Coffea canephora.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY
(2022)
Review
Infectious Diseases
Mazdida Sulaiman, Khoshnur Jannat, Veeranoot Nissapatorn, Mohammed Rahmatullah, Alok K. Paul, Maria de Lourdes Pereira, Mogana Rajagopal, Monica Suleiman, Mark S. Butler, Mohammed Khaled Bin Break, Jean-Frederic Weber, Polrat Wilairatana, Christophe Wiart
Summary: This review identified 141 alkaloids with antibacterial and/or antifungal activities from Asian angiosperms, and analyzed their distribution, molecular weights, solubility, and modes of action. Several alkaloids exhibited high activity and are potential lead molecules for development.
Article
Multidisciplinary Sciences
Plaipol Dedvisitsakul, Kanchana Watla-iad
Summary: This study evaluated the potential of some Thai edible plants in terms of their antioxidant activity and inhibitory effects on diabetic complications. The results showed that Caesalpinia mimosoides and Glochidion hirsutum had the highest phenolic and flavonoid content, respectively, while Schinus terebinthifolius had the highest antioxidant activity. Basella alba and S. terebinthifolius exhibited the strongest inhibitory activities against alpha-amylase and alpha-glycosidase, respectively. The extracts of Glochidion hirsutum and Polygonum odoratum showed stronger inhibitory effects on AGEs formation from glucose compared to the common drug aminoguanidine. The selected extracts in this study demonstrated their potential applications for the prevention of diabetes and its complications through the inhibitory effects on alpha-amylase, alpha-glycosidase, AGEs formation, and oxidative stress.
Article
Chemistry, Medicinal
Yuan-Hua Wang, Huai-Huai Dong, Fei Zhao, Jie Wang, Fang Yan, Yuan-Ying Jiang, Yong-Sheng Jin
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2016)
Article
Biochemistry & Molecular Biology
Yi-Xin Xu, Zhao-Bao Xiang, Yong-Sheng Jin, Wen Xu, Lian-Na Sun, Wan-Sheng Chen, Hai-Sheng Chen
CHEMISTRY & BIODIVERSITY
(2016)
Article
Plant Sciences
Yi-Xi Yang, Mao-Mao An, Yong-Sheng Jin, Hai-Sheng Chen
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2017)
Article
Biotechnology & Applied Microbiology
Xi-Jing Qian, Yong-Sheng Jin, Hai-Sheng Chen, Qing-Qiang Xu, Hao Ren, Shi-Ying Zhu, Hai-Lin Tang, Yan Wang, Ping Zhao, Zhong-Tian Qi, Yong-Zhe Zhu
JOURNAL OF GENERAL VIROLOGY
(2016)
Article
Chemistry, Medicinal
Hong-Chuan Liu, Zhao-Bao Xiang, Qiang Wang, Bo-Yan Li, Yong-Sheng Jin, Hai-Sheng Chen
Article
Biochemistry & Molecular Biology
Fei Zhao, Huai-Huai Dong, Yuan-Hua Wang, Tian-Yi Wang, Ze-Hao Yan, Fang Yan, Da-Zhi Zhang, Ying-Ying Cao, Yong-Sheng Jin
Article
Biochemical Research Methods
Yue Liu, Shan Lu, Liang Zhao, Xin Dong, Zhenyu Zhu, Yongsheng Jin, Haisheng Chen, Feng Lu, Zhanying Hong, Yifeng Chai
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2018)
Article
Chemistry, Medicinal
Kai-Xia Zhang, Wei Wang, Fei Zhao, Qing-Guo Meng, Yong-Sheng Jin
CHEMISTRY OF NATURAL COMPOUNDS
(2018)
Article
Chemistry, Medicinal
Junqi Wu, Tingjunhong Ni, Xiaoyun Chai, Ting Wang, Hongrui Wang, Jindong Chen, Yongsheng Jin, Dazhi Zhang, Shichong Yu, Yuanying Jiang
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2018)
Article
Chemistry, Multidisciplinary
Tingjunhong Ni, Lei Pang, Zhan Cai, Fei Xie, Zichao Ding, Yumeng Hao, Ran Li, Shichong Yu, Xiaoyun Chai, Ting Wang, Yongsheng Jin, Dazhi Zhang, Yuanying Jiang
JOURNAL OF SAUDI CHEMICAL SOCIETY
(2019)
Review
Chemistry, Medicinal
Yong-Sheng Jin
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2019)
Article
Plant Sciences
Xin Fang, Qiang Ma, Kai-Xia Zhang, Song-Yun Yao, Yi Feng, Yong-Sheng Jin, Shuang Liang
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
(2020)
Article
Chemistry, Medicinal
Zhan Cai, Zichao Ding, Yumeng Hao, Tingjunhong Ni, Fei Xie, Jing Zhao, Ran Li, Shichong Yu, Ting Wang, Xiaoyun Chai, Yongsheng Jin, Yue Gao, Dazhi Zhang, Yuanying Jiang
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2017)
Article
Pharmacology & Pharmacy
Liang-Jun Guo, Li-Ping Xu, Wei Zheng, Jia-Xiao Dong, Xian-Hui Yi, Yong-Sheng Jin
LATIN AMERICAN JOURNAL OF PHARMACY
(2017)
Article
Chemistry, Medicinal
Fei Xie, Tingjunhong Ni, Jing Zhao, Lei Pang, Ran Li, Zhan Cai, Zichao Ding, Ting Wang, Shichong Yu, Yongsheng Jin, Dazhi Zhang, Yuanying Jiang
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
(2017)
