Synthesis of steroids with nitrogen-containing substituents in ring D (Review)

Aromatase inhibitors and xenograft studies

(2011) Saranya Chumsri et al.   STEROIDS

Azido analogs of neuroactive steroids

(2011) Lukáš Vidrna et al.   STEROIDS

Synthesis of novel steroidal 17α-triazolyl derivatives via Cu(I)-catalyzed azide-alkyne cycloaddition, and an evaluation of their cytotoxic activity in vitro

(2011) Éva Frank et al.   STEROIDS

Efficient syntheses of 17-β-amino steroids

(2011) Scott D. Taylor et al.   STEROIDS

Synthesis, in vitro antifungal activity and mechanism of action of four sterol hydrazone analogues against the dimorphic fungus Paracoccidioides brasiliensis

(2011) Gonzalo Visbal et al.   STEROIDS

20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth

(2010) Manolis A. Fousteris et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small-Molecule Inhibitors of the Hedgehog Signaling Pathway as Cancer Therapeutics

(2010) Stefan Peukert et al.   ChemMedChem

Ursodeoxycholic Acid Amides As Novel Glucocorticoid Receptor Modulators

(2010) Ruchika Sharma et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Biomimetic Approach to C-nor-D-homo-Steroids

(2010) Philipp Heretsch et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Synthesis and neuromuscular blocking activity of 16-(2- and 3-pyridylmethylene) dehydroepiandrosterone derivatives

(2010) Sonal Dubey et al.   STEROIDS

Probing the binding pocket of the active site of aromatase with 2-phenylaliphatic androsta-1,4-diene-3,17-dione steroids

(2010) Madoka Takahashi et al.   STEROIDS

D-ring substituted 1,2,3-triazolyl 20-keto pregnenanes as potential anticancer agents: Synthesis and biological evaluation

(2010) Abid H. Banday et al.   STEROIDS

Studies on novel D-ring substituted steroidal pyrazolines as potential anticancer agents

(2010) Abid H. Banday et al.   STEROIDS

Synthesis and biological evaluation of some nitrogen containing steroidal heterocycles

(2010) Mervat M. Abdelhalim et al.   STEROIDS

Synthesis of Cyclopamine Using a Biomimetic and Diastereoselective Approach

(2009) Athanassios Giannis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis

(2009) Delphine Renard et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Aromatase inactivation by 2-substituted derivatives of the suicide substrate androsta-1,4-diene-3,17-dione

(2009) Madoka Takahashi et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Design and Synthesis of Inhibitors of Hedgehog Signaling Based on the Alkaloid Cyclopamine

(2009) Jeffrey D. Winkler et al.   ORGANIC LETTERS

Synthesis of All Diastereomers of the Piperidine−Alkaloid Substructure of Cyclopamine

(2009) Philipp Heretsch et al.   ORGANIC LETTERS

Steroselective synthesis of some steroidal oxazolines, as novel potential inhibitors of 17α-hydroxylase-C17,20-lyase

(2009) Dóra Ondré et al.   STEROIDS

Highly stereoselective synthesis of steroidal 2,5-diketopiperazines based on isocyanide chemistry

(2009) Andrea C. Bruttomesso et al.   TETRAHEDRON LETTERS

Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer

(2008) Srinivas K. Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and anticancer activity studies of cyclopamine derivatives

(2008) Jianjun Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Modulating G-Protein Coupled Receptor/G-Protein Signal Transduction by Small Molecules Suggested by Virtual Screening

(2008) Christina M. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in azasteroids chemistry

(2008) Malika Ibrahim-Ouali et al.   STEROIDS

Neighboring group participation

(2008) Dóra Ondré et al.   STEROIDS

Synthesis of novel C17 steroidal carbamates

(2008) Vânia M.A. Moreira et al.   STEROIDS

The synthesis of 13α-androsta-5,16-diene derivatives with carboxylic acid, ester and carboxamido functionalities at position-17 via palladium-catalyzed carbonylation

(2008) Péter Ács et al.   STEROIDS

Lathosterol side chain amides—A new class of human lathosterol oxidase inhibitors

(2007) Martin Giera et al.   STEROIDS

Synthesis of novel steroidal D-ring substituted isoxazoline derivatives of 17-oxoandrostanes

(2007) Abid H. Banday et al.   STEROIDS

Synthesis of some epoxy and/or N-oxy 17-picolyl and 17-picolinylidene-androst-5-ene derivatives and evaluation of their biological activity

(2007) Evgenija Djurendić et al.   STEROIDS