4.3 Article

Synergetic Activation of Lipase by an Amino Acid with Alkyl-PEG Sulfate Ionic Liquid

Journal

CHEMISTRY LETTERS
Volume 42, Issue 6, Pages 663-665

Publisher

CHEMICAL SOC JAPAN
DOI: 10.1246/cl.130171

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology of Japan [23360369]
  2. Tottori Prefecture
  3. Grants-in-Aid for Scientific Research [25550091, 23360369] Funding Source: KAKEN

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The synergetic effect of amino acids and an ionic liquid, 1-butyl-2,3-dimethylimidazolium alpha-cetylpolyoxyethylene(10) ether sulfate (IL1), as coating materials on lipase was discovered: coating on lipase PS using a certain amino acid with IL1 was found to be very effective for accelerating the lipase-catalyzed transesterification of secondary alcohols while maintaining perfect enantioselectivity.

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