Enhanced Adsorption of Protein Fused with Polymeric Material-binding Peptide

A model protein was fused with the ELWRPTR peptide, which binds specifically to the isotactic poly(methyl methacrylate) (it-PMMA) film surface, and its adsorption on PMMA film surfaces was then investigated by surface plasmon resonance measurements. We found that the adsorption constant of the fusion protein for the it-PMMA film surface was 75-fold greater than that of native protein.