Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase δ revealed in individual cells by cytometry

(2015) Zbigniew Darzynkiewicz et al.   Oncotarget

Suberoylanilide hydroxamic acid (SAHA) enhances olaparib activity by targeting homologous recombination DNA repair in ovarian cancer

(2014) Panagiotis A. Konstantinopoulos et al.   GYNECOLOGIC ONCOLOGY

Human T-cell leukaemia virus type I and adult T-cell leukaemia-lymphoma

(2014) Kenji Ishitsuka et al.   LANCET ONCOLOGY

Tax impairs DNA replication forks and increases DNA breaks in specific oncogenic genome regions

(2014) Hassiba Chaib-Mezrag et al.   Molecular Cancer

Base Excision Repair Defects Invoke Hypersensitivity to PARP Inhibition

(2014) Julie K. Horton et al.   MOLECULAR CANCER RESEARCH

Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors

(2014) Ciara C. O’Sullivan et al.   Frontiers in Oncology

PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies

(2013) J.-m. Lee et al.   ANNALS OF ONCOLOGY

Biology and treatment of HTLV-1 associated T-cell lymphomas

(2013) Kunihiro Tsukasaki et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Identification of miRNA modulators to PARP inhibitor response

(2013) Sari Neijenhuis et al.   DNA REPAIR

Resveratrol suppresses cell proliferation via inhibition of STAT3 phosphorylation and Mcl-1 and cIAP-2 expression in HTLV-1-infected T cells

(2013) Yuzo Suzuki et al.   LEUKEMIA RESEARCH

Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1

(2012) S. Ying et al.   CANCER RESEARCH

Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment

(2012) Lenka Oplustilova et al.   CELL CYCLE

Enhancement of Synthetic Lethality via Combinations of ABT-888, a PARP Inhibitor, and Carboplatin In Vitro and In Vivo Using BRCA1 and BRCA2 Isogenic Models

(2012) C. C. Clark et al.   MOLECULAR CANCER THERAPEUTICS

HTLV-I Tax Increases Genetic Instability by Inducing DNA Double Strand Breaks during DNA Replication and Switching Repair to NHEJ

(2012) Hicham H. Baydoun et al.   PLoS One

Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1 -Mutated Mouse Mammary Tumors

(2012) Janneke E. Jaspers et al.   Cancer Discovery

New insight into the oncogenic mechanism of the retroviral oncoprotein Tax

(2012) Hua Cheng et al.   Protein & Cell

Molecular mechanisms of HTLV-1 infection and pathogenesis

(2011) Junichiro Yasunaga et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy

(2011) M. Javle et al.   Therapeutic Advances in Medical Oncology

HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes

(2010) M. Bellon et al.   BLOOD

Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia

(2010) J. Pancewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

(2009) T. J. Gaymes et al.   HAEMATOLOGICA

Anticancer Effects of Phenoxazine Derivatives Revealed by Inhibition of Cell Growth and Viability, Disregulation of Cell Cycle, and Apoptosis Induction in HTLV-1–Positive Leukemia Cells

(2009) Naoko Miyano-Kurosaki et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Definition, Prognostic Factors, Treatment, and Response Criteria of Adult T-Cell Leukemia-Lymphoma: A Proposal From an International Consensus Meeting

(2008) Kunihiro Tsukasaki et al.   JOURNAL OF CLINICAL ONCOLOGY