Article
Nutrition & Dietetics
Ciniselli Chiara Maura, Bruno Eleonora, Oliverio Andreina, Baldassari Ivan, Pastori Marta, Signoroni Stefano, Vitellaro Marco, Ricci Maria Teresa, Milione Massimo, Cattaneo Laura, Gariboldi Manuela, Mancini Andrea, Rivoltini Licia, Morelli Daniele, Pasanisi Patrizia, Verderio Paolo
Summary: The study showed that adhering to a low-inflammatory Mediterranean diet can significantly reduce the number of diarrheal discharges in FAP patients, while also demonstrating good adherence to reducing the intake of foods not recommended and increasing the consumption of recommended foods.
Review
Nutrition & Dietetics
Siyuan Sun, Yingxue Han, Yumei Lei, Yifei Yu, Yanbin Dong, Juan Chen
Summary: This review comprehensively summarizes the intrinsic factors involved in the regulation of hematopoietic stem cells (HSCs), including RNA-binding protein, modulators in epigenetics, and enhancer-promotor-mediated transcription. It also explores their roles in bone marrow transplantation therapies and autoimmune diseases. Additionally, it discusses the effects of high-fat diets and nutrients (such as vitamins, amino acids, probiotics, and prebiotics) on HSC regulation, providing valuable insights for future HSC research.
Review
Food Science & Technology
Francisco Gomez-Delgado, Niki Katsiki, Jose Lopez-Miranda, Pablo Perez-Martinez
Summary: Preventing unhealthy dietary habits and lack of physical activity is crucial in managing dyslipidemia, with scientific societies recommending adherence to healthy dietary patterns and increased exercise. These nutritional and lifestyle recommendations can prevent cardiovascular disease and effectively manage cardiometabolic risk factors.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Nutrition & Dietetics
Monika Grabia, Renata Markiewicz-Zukowska, Joanna Bielecka, Anna Puscion-Jakubik, Katarzyna Socha
Summary: The study showed that through dietary education, young soccer players were able to improve their dietary habits, increase intake of digestible carbohydrates and dietary fiber, as well as improve fluid intake and hydration habits around workouts. Some participants reported faster recovery and overall better well-being as a result.
Review
Nutrition & Dietetics
Elizabeth A. A. Reznikov, David L. L. Suskind
Summary: Inflammatory Bowel Disease (IBD) is a group of chronic immune-mediated intestinal diseases associated with the interaction between the immune system and the intestinal microbiome. Nutritional therapy is supported in IBD but not commonly used in clinical practice. This literature review aims to enhance the understanding of diet's impact on IBD, focusing on Crohn's Disease (CD) and Ulcerative Colitis (UC). The contribution of diet to the development and treatment of IBD is significant, with nutritional interventions improving symptoms and inflammation burden.
Review
Endocrinology & Metabolism
Elien Alderweireldt, Charlotte Grootaert, Olivier De Wever, John Van Camp
Summary: This review discusses how the two-front environment affects the bioenergetic status of colonocytes throughout the development of colorectal cancer (CRC) and explores dietary strategies that target the specific metabolic preferences of CRC cells, potentially influencing their bioenergetics and outcome.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2022)
Article
Nutrition & Dietetics
Ewa Karpecka-Galka, Paulina Mazur-Kurach, Zbigniew Szygula, Barbara Fraczek
Summary: Appropriate nutritional preparation is crucial for high-mountain expeditions. However, there are issues with the dietary habits of high mountain climbers, such as inadequate protein intake and excessive fat intake. It is necessary to develop nutritional and supplementation guidelines to improve the health and performance of climbers in high-mountain conditions.
Article
Nutrition & Dietetics
Izabela Kwiatkowska, Jakub Olszak, Piotr Formanowicz, Dorota Formanowicz
Summary: The study found that individuals with different dietary habits showed variations in consumption frequency of certain foods, with omnivores and pescatarians consuming more sweets and dairy products, while vegans and vegetarians consumed more legumes and nuts. Body composition analysis revealed that vegetarians had higher skeletal muscle mass and mineral content compared to omnivores and pescatarians.
Article
Nutrition & Dietetics
Diogo Vale, Clelia de Oliveira Lyra, Natalie Marinho Dantas, Maria Eduarda da Costa Andrade, Angelo Giuseppe Roncalli da Costa Oliveira
Summary: Brazilian adolescents have diverse dietary and nutritional profiles, which are influenced by sociopolitical and economic contexts, family material and school circumstances, and the behavioral and psychosocial health factors of individuals.
Review
Nutrition & Dietetics
Javier Molina-Infante
Summary: The step-up empiric elimination diet is the gold standard for treating EoE patients. Milk, wheat, and egg are the most common triggers for EoE. Elimination diets with restrictions on four food groups may be suitable for highly motivated patients, but nutritional counseling is advised. Malnourishment is uncommon in EoE patients, but may be influenced by factors such as other gastrointestinal disorders and feeding difficulties.
Article
Nutrition & Dietetics
Marta Suarez-Gonzalez, Carlos Bousono-Garcia, Santiago Jimenez-Trevino, Juan Jose Diaz-Martin
Summary: A study found that counseling with a registered dietitian significantly improved dietary habits in pediatric celiac patients, leading to better compliance with dietary reference values, reduced intake of red meat and ultra-processed foods, increased intake of fruits and vegetables, decreased saturated fat and sugar intake, and promoted normal bowel habits.
Review
Oncology
Rosario Mazzola, Francesco Cuccia, Alessandro Bertani, Slavisa Tubin, Pier Giulio Conaldi, Stefanie Corradini, Maria Tolia, Markus Guba, Filippo Alongi
Summary: Radiotherapy in cancer patients with prior organ transplants poses challenges due to potential effects on immunosuppressive therapy and organ tolerance. This systematic review aims to assess the safety and efficacy of radiotherapy in these patients, focusing on modern treatment techniques.
Review
Nutrition & Dietetics
Dominika Jamiol-Milc, Anna Gudan, Karolina Kazmierczak-Siedlecka, Joanna Holowko-Ziolek, Dominika Maciejewska-Markiewicz, Katarzyna Janda-Milczarek, Ewa Stachowska
Summary: The liver plays a crucial role in the metabolism of nutrients and the storage of micronutrients, but chronic liver diseases can lead to nutritional deficiencies and poor prognosis. This review focuses on the dietary therapy for patients with chronic liver diseases, including those eligible for liver transplantation and in the postoperative period.
Review
Nutrition & Dietetics
Jun-Ming Lim, Vengadesh Letchumanan, Loh Teng-Hern Tan, Kar-Wai Hong, Sunny-Hei Wong, Nurul-Syakima Ab Mutalib, Learn-Han Lee, Jodi Woan-Fei Law
Summary: The ketogenic diet has been utilized since the 1920s as an effective treatment for epilepsy and other neurological diseases. It is now being explored for its potential impact on the gut microbiome, which is believed to play a role in these diseases. The current information suggests that the ketogenic diet can alter the gut microbiome and improve disease symptoms.
Article
Nutrition & Dietetics
Sinead Watson, Leigh-Ann McCrum, Bernadette McGuinness, Christopher Cardwell, Mike Clarke, Jayne V. Woodside, Gerry McKenna, Laura McGowan
Summary: An RCT showed that a habit-based dietary intervention after oral rehabilitation increased automaticity for healthy eating behaviors in older adults, presenting significant nutritional challenges for partially dentate adults in an ageing population.
Article
Cardiac & Cardiovascular Systems
Joshua Saef, Trejeeve Martyn, Lauren Ives, Lori R. Roth, Justin L. Grodin, Mathew S. Maurer, Mazen Hanna, W. H. Wilson Tang
Summary: Using age, sex, and race as factors, it is possible to accurately determine whether patients with ATTR-CM carry pathogenic TTR gene mutations. Non-Black patients aged 69 years and older diagnosed with ATTR-CM have a low likelihood of having ATTRv.
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Pieter Martens, Sanjeeb Bhattacharya, Joshua Longinow, Lauren Ives, Miriam Jacob, Jason Valent, Mazen Hanna, W. H. Wilson Tang
Summary: This study analyzed the prognostic relevance of cardiac hemodynamic cutoffs in cardiac amyloidosis (CA) and its subtypes. The results showed that the classic hemodynamic cutoff values were not effective in identifying adverse outcomes, but higher values performed better. Reduced cardiac index was strongly associated with adverse outcomes and independently predicted risk. The study suggested that hemodynamic variables are abnormal in CA, and elevated filling pressures at higher threshold values are prognostic.
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Bryan Q. Abadie, Nicholas Chan, Zarina Sharalaya, Pavan Bhat, Serge Harb, Miriam Jacob, Randall C. Starling, W. H. Wilson Tang, Paul C. Cremer, Wael A. Jaber
Summary: This study validates the diagnostic and prognostic value of an algorithm using PET/CT scanning with myocardial blood flow (MBF) for cardiac allograft vasculopathy (CAV). PET CAV 0 has a high negative predictive value for moderate to severe CAV, while PET CAV 2/3 has a high positive predictive value. PET/CT scanning with MBF is a reasonable alternative to invasive coronary angiography for CAV screening.
JACC-HEART FAILURE
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
W. H. Wilson Tang, Weili Zheng
CIRCULATION-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Pieter Martens, Shilin Yu, Brett Larive, Barry A. Borlaug, Serpil C. Erzurum, Samar Farha, J. Emanuel Finet, Gabriele Grunig, Anna R. Hemnes, Nicholas S. Hill, Evelyn M. Horn, Miriam Jacob, Deborah H. Kwon, Margaret M. Park, Franz P. Rischard, Erika B. Rosenzweig, Jennifer D. Wilcox, Wai Hong Wilson Tang
Summary: Iron deficiency is common in pulmonary hypertension, but its clinical significance and optimal definition remain unclear. This study analyzed data from 1028 patients and found that the heart failure definition of iron deficiency endorsed by pulmonary hypertension guidelines did not identify patients with lower exercise capacity or functional status. However, defining iron deficiency as transferrin saturation (TSAT) <21% identified patients with lower exercise capacity, worse functional status, right heart remodeling, and adverse clinical outcomes.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Robert A. Montgomery, Joseph Mauch, Parvathy Sankar, Trejeeve Martyn, Tim Engelman, Pieter Martens, Kathleen Faulkenberg, Venu Menon, Jerry D. Estep, W. h. Wilson Tang
Summary: This study compared the safety and efficacy of oral sodium chloride versus placebo during intravenous diuretic therapy in patients with acute heart failure. The results showed no significant difference between the two groups in terms of improving renal function and weight.
JOURNAL OF CARDIAC FAILURE
(2023)
Review
Cardiac & Cardiovascular Systems
Petra Mamic, Michael Snyder, W. H. Wilson Tang
Summary: Despite therapeutic advances, chronic heart failure (HF) still poses significant risks. Precision medicine approaches, especially in understanding the role of gut microbiome dysregulation, have the potential to provide novel biomarkers, therapeutic targets, and improved disease risk stratification. Deeper insights into gut microbiome-host interactions may pave the way toward personalized HF care and improved clinical outcomes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Health Care Sciences & Services
Sahana Aiyer, Emilia Kalutskaya, Arianne C. Agdamag, W. H. Wilson Tang
Summary: Cardiomyopathy, a leading cause of heart failure, can be caused by abnormalities in the heart muscles that affect its ability to pump blood effectively. Genetic screening and counseling play a crucial role in identifying potential monogenic causes of cardiomyopathy, enabling early intervention and personalized treatment. Cascade testing and risk stratification can help identify at-risk family members and address variants of uncertain significance. This review focuses on the importance of clinical genetic testing for various types of cardiomyopathies, early detection and treatment, family screening, personalized treatment approaches, and current strategies for genetic testing outreach.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Erika Hutt, Maria Vega Brizneda, Ghazaleh Goldar, Jose Aguilera, Tom Kai Ming Wang, Ziad Taimeh, Daniel Culver, Thomas Callahan, W. H. Wilson Tang, Paul C. Cremer, Wael A. Jaber, Manuel L. Ribeiro Neto, Christine L. Jellis
Summary: In patients with cardiac sarcoidosis, a mild reduction in left ventricular ejection fraction (LVEF) of 42% was identified as the optimal cutoff for predicting ventricular arrhythmia (VA) and all-cause mortality. Prior occurrence of VA and the presence of scar in cardiac magnetic resonance (CMR) or positron emission tomography (PET) are strong risk factors for future VA and mortality.
Editorial Material
Cardiac & Cardiovascular Systems
W. H. Wilson Tang, Wolfgang Koenig
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Pieter Martens, Leslie T. Cooper, W. H. Wilson Tang
Summary: Myocarditis is most commonly recognized in patients with moderate to severe, recent-onset heart failure. However, less typical presentations including myocardial infarction with normal coronary arteries and arrhythmias are important but less commonly recognized manifestations of myocarditis. Identifying the risk and providing appropriate follow-up and management is crucial in myocarditis.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Thanat Chaikijurajai, Sevag Demirjian, W. H. Wilson Tang
Summary: This study aimed to investigate the association between increased baseline NT-proBNP levels and adverse renal outcomes in patients with moderate-to-severe acute kidney injury. The results showed that increased NT-proBNP levels were associated with an increased risk of dialysis requirement, becoming dialysis dependent, and in-hospital mortality.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Nandan Kodur, Salva Yurista, Valesha Province, Emma Rueth, Christopher Nguyen, W. H. Wilson Tang
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Pieter Martens, Silvio N. Augusto, J. Emanuel Finet, W. H. Wilson Tang
Summary: Noncardiac comorbidities significantly affect exercise capacity and functional status in patients with chronic heart failure, with certain clusters of comorbidities having a more pronounced impact on outcomes. The type and burden of NCCs in HF patients play a crucial role in determining clinical outcomes and the response to aerobic exercise training.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Brian Hsi, Valesha Province, W. H. Wilson Tang
Summary: The purpose of this review is to emphasize the significance of frailty in the care of patients with advanced heart failure. It discusses the available data for assessing frailty in these patients and the challenges involved in doing so.
CURRENT TREATMENT OPTIONS IN CARDIOVASCULAR MEDICINE
(2023)