Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s

Title
Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s
Authors
Keywords
-
Journal
CHEMICO-BIOLOGICAL INTERACTIONS
Volume 173, Issue 1, Pages 59-67
Publisher
Elsevier BV
Online
2008-03-04
DOI
10.1016/j.cbi.2008.02.001

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