Glycopolymer probes of signal transduction

Carbohydrate-PNA and Aptamer-PNA Conjugates for the Spatial Screening of Lectins and Lectin Assemblies

(2013) Christian Scheibe et al.   CHEMBIOCHEM

Noncarbohydrate Glycomimetics and Glycoprotein Surrogates as DC-SIGN Antagonists and Agonists

(2012) Lynne R. Prost et al.   ACS Chemical Biology

Glycobiology of immune responses

(2012) Gabriel A. Rabinovich et al.   Annals of the New York Academy of Sciences

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Cellular Uptake of Gold Nanoparticles Bearing HIV gp120 Oligomannosides

(2012) Blanca Arnáiz et al.   BIOCONJUGATE CHEMISTRY

Designed Ankyrin Repeat Proteins as Scaffolds for Multivalent Recognition

(2012) Jessica J. Hollenbeck et al.   BIOMACROMOLECULES

BODIPY-Labeled DC-SIGN-Targeting Glycodendrons Efficiently Internalize and Route to Lysosomes in Human Dendritic Cells

(2012) Renato Ribeiro-Viana et al.   BIOMACROMOLECULES

Sequence-Defined Glycopolymer Segments Presenting Mannose: Synthesis and Lectin Binding Affinity

(2012) Daniela Ponader et al.   BIOMACROMOLECULES

In vivo targeting of alveolar macrophages via RAFT-based glycopolymers

(2012) Eun-Ho Song et al.   BIOMATERIALS

Synthesis of Glycopolymers by Controlled Radical Polymerization Techniques and Their Applications

(2012) Vimary Vázquez-Dorbatt et al.   CHEMBIOCHEM

Micelles based on gold-glycopolymer complexes as new chemotherapy drug delivery agents

(2012) Samuel Pearson et al.   CHEMICAL COMMUNICATIONS

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications

(2012) Nicolas Spinelli et al.   CHEMICAL SOCIETY REVIEWS

Multivalent glycoconjugates as anti-pathogenic agents

(2012) Anna Bernardi et al.   CHEMICAL SOCIETY REVIEWS

Multivalent Gold Glycoclusters: High Affinity Molecular Recognition by Bacterial Lectin PA-IL

(2012) Michael Reynolds et al.   CHEMISTRY-A EUROPEAN JOURNAL

Innate Immunity Mediates Follicular Transport of Particulate but Not Soluble Protein Antigen

(2012) A. Link et al.   JOURNAL OF IMMUNOLOGY

A Peptide Nucleic Acid–Aminosugar Conjugate Targeting Transactivation Response Element of HIV-1 RNA Genome Shows a High Bioavailability in Human Cells and Strongly Inhibits Tat-Mediated Transactivation of HIV-1 Transcription

(2012) Indrajit Das et al.   JOURNAL OF MEDICINAL CHEMISTRY

Control of Protein-Binding Kinetics on Synthetic Polymer Nanoparticles by Tuning Flexibility and Inducing Conformation Changes of Polymer Chains

(2012) Yu Hoshino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Glycopolymer Code: Synthesis of Glycopolymers and Multivalent Carbohydrate-Lectin Interactions

(2012) C. Remzi Becer   MACROMOLECULAR RAPID COMMUNICATIONS

Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells

(2012) Juan J. García-Vallejo et al.   MOLECULAR IMMUNOLOGY

A sulfated carbohydrate epitope inhibits axon regeneration after injury

(2012) J. M. Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds

(2012) Ethan A. Englund et al.   Nature Communications

Mechanism of Multivalent Carbohydrate-Protein Interactions Studied by EPR Spectroscopy

(2011) Patrick Braun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycan Microarrays for Decoding the Glycome

(2011) Cory D. Rillahan et al.   Annual Review of Biochemistry

Synthesis of glycopeptide dendrimers, dimerization and affinity for Concanavalin A

(2011) Ronan Euzen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Defined Presentation of Carbohydrates on a Duplex DNA Scaffold

(2011) Mark K. Schlegel et al.   CHEMBIOCHEM

Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells

(2011) Mihai Ciobanu et al.   CHEMICAL COMMUNICATIONS

N-Acetyl-d-glucosamine-coated polyamidoamine dendrimer promotes tumor-specific B cell responses via natural killer cell activation

(2011) Katarina Hulikova et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

End-Group Distributions of Multiple Generations of Spin-Labeled PAMAM Dendrimers

(2011) Karl B. Sebby et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Thiol-alkyne Chemistry for the Preparation of Micelles with Glycopolymer Corona: Dendritic Surfaces versus Linear Glycopolymer in Their Ability to Bind to Lectins

(2011) Jatin Kumar et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Mannose-Functionalized “Pathogen-like” Polyanhydride Nanoparticles Target C-Type Lectin Receptors on Dendritic Cells

(2011) Brenda Carrillo-Conde et al.   MOLECULAR PHARMACEUTICS

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

6-Sulphated Chondroitins Have a Positive Influence on Axonal Regeneration

(2011) Rachel Lin et al.   PLoS One

Architecture effects on L-selectin shedding induced by polypeptide-based multivalent ligands

(2011) Shuang Liu et al.   Polymer Chemistry

Synthesis of thermo-responsive glycopolymers via copper catalysed azide–alkyne ‘click’ chemistry for inhibition of ricin: the effect of spacer between polymer backbone and galactose

(2011) Jatin Kumar et al.   Polymer Chemistry

Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida

(2011) P.-C. Pang et al.   SCIENCE

Architecturally Complex Polymers with Controlled Heterogeneity

(2011) K. Matyjaszewski   SCIENCE

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Quinoxalinoneinhibitors of the lectin DC-SIGN

(2011) Shane L. Mangold et al.   Chemical Science

Inhibition of DC-SIGN-Mediated HIV Infection by a Linear Trimannoside Mimic in a Tetravalent Presentation

(2010) Sara Sattin et al.   ACS Chemical Biology

A Synthetic “Tour de Force”: Well-Defined Multivalent and Multimodal Dendritic Structures for Biomedical Applications

(2010) Lars Röglin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Approaches to Glycobiology

(2010) Laura L. Kiessling et al.   Annual Review of Biochemistry

Synthesis and Immunogenicity of a Glycopolymer Conjugate

(2010) Tomasz Lipinski et al.   BIOCONJUGATE CHEMISTRY

Synthesis of a family of amphiphilic glycopolymers via controlled ring-opening polymerization of functionalized cyclic carbonates and their application in drug delivery

(2010) Fabian Suriano et al.   BIOMATERIALS

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

(2010) Urban Švajger et al.   CELLULAR SIGNALLING

A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN

(2010) Kathleen C. A. Garber et al.   CHEMICAL COMMUNICATIONS

Synthesis of Multivalent Tuberculosis andLeishmania-Associated Capping Carbohydrates Reveals Structure-Dependent Responses Allowing Immune Evasion

(2010) Eun-Ho Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Affinity Glycopolymer Binding to Human DC-SIGN and Disruption of DC-SIGN Interactions with HIV Envelope Glycoprotein

(2010) C. Remzi Becer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Lectin Recognition of Glyco Star Polymers Prepared by “Clicking” Thiocarbohydrates onto a Reactive Scaffold

(2010) Yong Chen et al.   MACROMOLECULES

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands

(2010) David Deniaud et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of glycopolymers and their multivalent recognitions with lectins

(2010) S. R. Simon Ting et al.   Polymer Chemistry

A spoonful of sugar: the application of glycopolymers in therapeutics

(2010) Sebastian G. Spain et al.   Polymer Chemistry

Synthesis and Microcontact Printing of Dual End-Functionalized Mucin-like Glycopolymers for Microarray Applications

(2009) Kamil Godula et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

(2009) Katarzyna Gorska et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

(2009) Narayanaswamy Jayaraman   CHEMICAL SOCIETY REVIEWS

Glycan arrays: recent advances and future challenges

(2009) Oyindasola Oyelaran et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Lectins as pattern recognition molecules: The effects of epitope density in innate immunity

(2009) T. K Dam et al.   GLYCOBIOLOGY

N-Acetyl-D-glucosamine-coated polyamidoamine dendrimer modulates antibody formation via natural killer cell activation

(2009) Katarina Hulikova et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo

(2009) Bao Hoa Duong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In VitroImaging andin VivoLiver Targeting with Carbohydrate Capped Quantum Dots

(2009) Raghavendra Kikkeri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Surface Functionalization of Nanomaterials with Dendritic Groups: Toward Enhanced Binding to Biological Targets

(2009) Amanda L. Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neoglycopolymers Based on 4-Vinyl-1,2,3-Triazole Monomers Prepared by Click Chemistry

(2009) Martin Hetzer et al.   MACROMOLECULAR BIOSCIENCE

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sialylated multivalent antigens engage CD22in transand inhibit B cell activation

(2009) Adam H. Courtney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTP  Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

(2009) Y. Shen et al.   SCIENCE

Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles

(2008) Xiaoling Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multivalent Carbohydrate Recognition on a Glycodendrimer‐Functionalized Flow‐Through Chip

(2008) Hilbert M. Branderhorst et al.   CHEMBIOCHEM

Globotriose-Functionalized Gold Nanoparticles as Multivalent Probes for Shiga-like Toxin

(2008) Yuh-Yih Chien et al.   CHEMBIOCHEM

Synthesis of Novel DC-SIGN Ligands with an α-Fucosylamide Anchor

(2008) Gabriele Timpano et al.   CHEMBIOCHEM

The Structure of Glycosaminoglycans and their Interactions with Proteins

(2008) Neha S. Gandhi et al.   Chemical Biology & Drug Design

Glycan arrays: biological and medical applications

(2008) Pi-Hui Liang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chondroitin-4-sulfation negatively regulates axonal guidance and growth

(2008) H. Wang et al.   JOURNAL OF CELL SCIENCE

Bifunctional CD22 Ligands Use Multimeric Immunoglobulins as Protein Scaffolds in Assembly of Immune Complexes on B Cells

(2008) Mary K. O’Reilly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Neuroactive Chondroitin Sulfate Glycomimetics

(2008) Manish Rawat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Involvement of Water in Carbohydrate−Protein Binding: Concanavalin A Revisited

(2008) Renuka Kadirvelraj et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY

The effect of particle design on cellular internalization pathways

(2008) S. E. A. Gratton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial chemoreceptors: high-performance signaling in networked arrays

(2008) Gerald L. Hazelbauer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Quantum dots – Nano-sized probes for the exploration of cellular and intracellular targeting

(2007) W.A. Hild et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission

(2007) Lot de Witte et al.   TRENDS IN MOLECULAR MEDICINE