Designing a new antifungal glycoconjugate vaccine

Design of a Candida albicans Disaccharide Conjugate Vaccine by Reverse Engineering a Protective Monoclonal Antibody

(2012) David R. Bundle et al.   ACS Chemical Biology

Synthesis of three trisaccharide congeners to investigate frame shifting of β1,2-mannan homo-oligomers in an antibody binding site

(2012) Casey Costello et al.   CARBOHYDRATE RESEARCH

Members 5 and 6 of the Candida albicans BMT family encode enzymes acting specifically on  -mannosylation of the phospholipomannan cell-wall glycosphingolipid

(2012) C. Mille et al.   GLYCOBIOLOGY

Molecular Recognition ofCandida albicans(1→2)-β-Mannan Oligosaccharides by a Protective Monoclonal Antibody Reveals the Immunodominance of Internal Saccharide Residues

(2012) Margaret A. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of a Candida albicans tetrasaccharide spanning the β1,2-mannan phosphodiester α-mannan junction

(2012) Anh-Thu Dang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Self-Adjuvanting Glycopeptide Conjugate Vaccine against Disseminated Candidiasis

(2012) Hong Xin et al.   PLoS One

Immunochemistry of pathogenic yeast, Candida species, focusing on mannan

(2012) Nobuyuki SHIBATA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam3CysSer

(2011) Brendan L. Wilkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C. albicans increases cell wall mannoprotein, but not mannan, in response to blood, serum and cultivation at physiological temperature

(2011) M. Kruppa et al.   GLYCOBIOLOGY

A structurally diversified linker enhances the immune response to a small carbohydrate hapten

(2011) Tomasz Lipinski et al.   GLYCOCONJUGATE JOURNAL

A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

(2011) Fikri Y Avci et al.   NATURE MEDICINE

New Insights into the Structure of (1→3,1→6)-β-D-Glucan Side Chains in the Candida glabrata Cell Wall

(2011) Douglas W. Lowman et al.   PLoS One

Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

(2011) V. Lakshminarayanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boosting antibody responses by targeting antigens to dendritic cells

(2011) Irina Caminschi et al.   TRENDS IN IMMUNOLOGY

The changing and dynamic epidemiology of meningococcal disease

(2011) Scott A. Halperin et al.   VACCINE

Immunochemical studies of Shigella flexneri 2a and 6, and Shigella dysenteriae type 1 O-specific polysaccharide-core fragments and their protein conjugates as vaccine candidates

(2010) Joanna Kubler-Kielb et al.   CARBOHYDRATE RESEARCH

Epidemiology of invasive candidiasis

(2010) Maiken C Arendrup   Current Opinion in Critical Care

‘Dressed for success’ C-type lectin receptors for the delivery of glyco-vaccines to dendritic cells

(2010) Wendy WJ Unger et al.   CURRENT OPINION IN IMMUNOLOGY

The epidemiology of meningococcal disease and the impact of vaccines

(2010) Ameneh Khatami et al.   Expert Review of Vaccines

Molecular Analysis of Carbohydrate−Antibody Interactions: Case Study Using aBacillus anthracisTetrasaccharide

(2010) Matthias A. Oberli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Beta-glucan-CRM197 conjugates as candidates antifungal vaccines

(2010) Carla Bromuro et al.   VACCINE

Prospects for Development of a Vaccine to Prevent and Control Vaginal Candidiasis

(2010) Paul L. Fidel et al.   Current Infectious Disease Reports

A Synthetic Vaccine Consisting of a Tumor-Associated Sialyl-TN-MUC1 Tandem-Repeat Glycopeptide and Tetanus Toxoid: Induction of a Strong and Highly Selective Immune Response

(2009) Anton Kaiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of monodeoxy and mono-O-methyl congeners of methyl β-d-mannopyranosyl-(1→2)-β-d-mannopyranoside for epitope mapping of anti-Candida albicans antibodies

(2009) Corwin M. Nycholat et al.   CARBOHYDRATE RESEARCH

Molecular Phenotyping of Mannosyltransferases-Deficient Candida albicans Cells by High-Resolution Magic Angle Spinning NMR

(2009) Emmanuel Maes et al.   JOURNAL OF BIOCHEMISTRY

A Synthetic Carbohydrate-Protein Conjugate Vaccine Candidate against Shigella flexneri 2a Infection

(2009) A. Phalipon et al.   JOURNAL OF IMMUNOLOGY

Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains

(2009) Jianglong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence

(2009) Antonella Torosantucci et al.   PLoS One

A Novel Linker Methodology for the Synthesis of Tailored Conjugate Vaccines Composed of Complex Carbohydrate Antigens and Specific TH‐Cell Peptide Epitopes

(2008) Sebastian Dziadek et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of a New Family of Genes Involved in β-1,2-Mannosylation of Glycans inPichia pastorisandCandida albicans

(2008) Céline Mille et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

C. albicans Colonization of Human Mucosal Surfaces

(2008) Peter Southern et al.   PLoS One

Synthetic glycopeptide vaccines combining  -mannan and peptide epitopes induce protection against candidiasis

(2008) H. Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody

(2008) B. Vulliez-Le Normand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA