Journal
CHEMICAL SOCIETY REVIEWS
Volume 41, Issue 21, Pages 6902-6915Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cs35158g
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2,5-Piperazinediones (2,5-diketopiperazines, DKPs) can be viewed as privileged building blocks for the synthesis of heterocyclic systems. This tutorial review aims at underscoring the large number and structural variety of nitrogen heterocycles that are available by suitable manipulation of DKP starting materials, including many bioactive compounds and natural products.
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