Designing polymeric particles for antigen delivery

A Protective Vaccine Delivery System for In Vivo T Cell Stimulation Using Nanoengineered Polymer Hydrogel Capsules

(2009) Amy Sexton et al.   ACS Nano

Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens

(2009) Stefaan De Koker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A paradigm for peptide vaccine delivery using viral epitopes encapsulated in degradable polymer hydrogel capsules

(2009) Siow-Feng Chong et al.   BIOMATERIALS

Mechanism of action of clinically approved adjuvants

(2009) Bart N Lambrecht et al.   CURRENT OPINION IN IMMUNOLOGY

Antigen presentation by dendritic cells in vivo

(2009) Elodie Segura et al.   CURRENT OPINION IN IMMUNOLOGY

Pulsed in vitro release and in vivo behavior of exploding microcapsules

(2009) Bruno G. De Geest et al.   JOURNAL OF CONTROLLED RELEASE

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapy

(2009) K. E. Broaders et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multilayer-derived, ultrathin, stimuli-responsive hydrogels

(2009) Veronika Kozlovskaya et al.   Soft Matter

A single step process for the synthesis of antigen laden thermosensitive microparticles

(2009) Bruno G. De Geest et al.   Soft Matter

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

(2008) Yuki Hori et al.   Acta Biomaterialia

Binding, Internalization, and Antigen Presentation of Vaccine-Loaded Nanoengineered Capsules in Blood

(2008) Robert De Rose et al.   ADVANCED MATERIALS

Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy

(2008) Yuki Hori et al.   BIOMATERIALS

The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cells

(2008) Kenny K. Tran et al.   BIOMATERIALS

Endocytosis mechanisms and the cell biology of antigen presentation

(2008) Sven Burgdorf et al.   CURRENT OPINION IN IMMUNOLOGY

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Alum adjuvanticity: Unraveling a century old mystery

(2008) Ennio De Gregorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo

(2008) Nancy Luckashenak et al.   IMMUNITY

The cell biology of cross-presentation and the role of dendritic cell subsets

(2008) Ming-Lee Lin et al.   IMMUNOLOGY AND CELL BIOLOGY

Monocyte-derived dendritic cells in innate and adaptive immunity

(2008) Beatriz León et al.   IMMUNOLOGY AND CELL BIOLOGY

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

(2008) Mirjam Kool et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity

(2008) Samar Hamdy et al.   VACCINE

TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses

(2008) Eva Schlosser et al.   VACCINE

Biodegradable microcapsules designed via ‘click’ chemistry

(2007) Bruno G. De Geest et al.   CHEMICAL COMMUNICATIONS