Cytochrome b5 Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases

Title
Cytochrome b5 Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases
Authors
Keywords
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Journal
CHEMICAL RESEARCH IN TOXICOLOGY
Volume 25, Issue 5, Pages 1075-1085
Publisher
American Chemical Society (ACS)
Online
2012-03-06
DOI
10.1021/tx3000335

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