Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel

Title
Metabolic Oxidative Cleavage of Thioesters: Evidence for the Formation of Sulfenic Acid Intermediates in the Bioactivation of the Antithrombotic Prodrugs Ticlopidine and Clopidogrel
Authors
Keywords
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Journal
CHEMICAL RESEARCH IN TOXICOLOGY
Volume 22, Issue 2, Pages 369-373
Publisher
American Chemical Society (ACS)
Online
2009-01-27
DOI
10.1021/tx8004828

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