Benzylic Oxidation of Gemfibrozil-1-O-β-Glucuronide by P450 2C8 Leads to Heme Alkylation and Irreversible Inhibition

Published 2009 View Full Article

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Title
Benzylic Oxidation of Gemfibrozil-1-O-β-Glucuronide by P450 2C8 Leads to Heme Alkylation and Irreversible Inhibition
Authors
Keywords
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Journal
CHEMICAL RESEARCH IN TOXICOLOGY
Volume 22, Issue 7, Pages 1298-1309
Publisher
American Chemical Society (ACS)
Online
2009-05-16
DOI
10.1021/tx900105n

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