Journal
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
Volume 29, Issue 4, Pages 682-685Publisher
HIGHER EDUCATION PRESS
DOI: 10.1007/s40242-013-3030-x
Keywords
Litchi chinensis Sonn. seed; Flavanoid; Inhibitory activity; alpha-Glucosidase
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Funding
- National Natural Science Foundation of China [30873370]
- Doctor Fund of Jilin Agricultural University of China [201210]
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With the bioactivity-guided method, a new flavanone glycoside, together with nine known flavonoids were isolated from 50% aqueous ethanol of litchi(Litchi chinensis Sonn.) seeds. The chemical structure of the new compound was elucidated via 1D and 2D nuclear magnetic resonance(NMR) techniques and mass spectrometry to be (2S)-pinocembrin-7-O-(6aEuro(3)-O-alpha-L-arabinosyl-beta-D-glucopyranoside)(1), and the nine known compounds were determined to be quercetin(2), phlorhizin(3), pinocembrin-7-O-glucoside(4), kaempferol-7-O-beta-D-glucopyranoside(5), onychin(6), nairutin(7), narcissin(8), pinocembrin-7-O-[(6aEuro(3)-O-beta-D-glucopyranoside)-beta-D-glucopyranoside](9) and pinocembrin-7-O-[(2aEuro(3),6aEuro(3)-di-O-alpha-L-rhamnopyranosyl)-beta-D-glucopyranoside](10). Some of the isolated flavonoids were tested for their inhibitory effects on alpha-glucosidase. And compounds 2 and 3 showed stronger inhibitory activity than positive control.
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