Article
Engineering, Electrical & Electronic
Guojun Liu, Meng Wang, Luntao Dong, Duanyi Zhu, Conghui Wang, Yanhui Jia, Xinbo Li, Jibo Wang
Summary: A novel Y-shaped split-and-recombine (SAR) micromixer is proposed, which demonstrates better mixing performance and smaller pressure loss due to its three-dimensional structure, splitting recombination, and chaotic convection mechanism. Simulation and experimental results show that the channel aspect ratio has a significant impact on the mixing performance and pressure loss of the micromixer. The micromixer has broad application prospects in chemical synthesis, biochemical analysis, and biomedicine.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Chemistry, Multidisciplinary
Junyao Wang, Xingyu Chen, Huan Liu, Yunpeng Li, Tianhong Lang, Rui Wang, Bowen Cui, Weihua Zhu
Summary: This paper presents a helical three-dimensional passive micromixer fabricated through 3D printing and polymer dissolution technology, which effectively improves the mixing efficiency according to experimental results.
Article
Nanoscience & Nanotechnology
Reza Karimi, Sajad Rezazadeh, Mohammad Raad
Summary: This paper presents a three-dimensional study of the nitrogen and oxygen mixing process in a T-type micromixer, and validates the improvement of mixing quality by introducing SAR structures. It is found that at low Reynolds numbers, the mixing quality is high, and increasing the cross-section area of mixing units can enhance mixing quality.
MICROFLUIDICS AND NANOFLUIDICS
(2021)
Article
Thermodynamics
Qiushi Chen, Mindi Zhang, Chen Zheng, Hansheng Li
Summary: This study systematically discusses the flow and geometric parameters of a novel micromixer with a self-designed repetitive SAR mixing element through numerical simulation and evaluation based on mixing index. The mixing performance of the SAR micromixer is compared with a conventional T-shaped micromixer, revealing that the SAR micromixer exhibits high mixing performance and has similar input power to the T-shaped micromixer.
HEAT TRANSFER ENGINEERING
(2023)
Article
Engineering, Chemical
Yudong Li, Shihan Wu, Yiqian Liu, Ning Wang, Pinyi Dai, Qiang Yang, Hao Lu
Summary: The development of high-performance static mixers is a critical research topic in process intensification in the process industry. This study successfully designed a new type of static micromixer using computational fluid dynamics simulation and experimental testing, achieving a dispersion effect and greatly improving static mixing efficiency through continuous optimization.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2022)
Article
Chemistry, Analytical
Ranjitsinha R. Gidde
Summary: This paper analyzed the mixing performance of three types of baffle-based passive micromixers using numerical simulation, finding different mixing mechanisms at different Reynolds numbers and their suitability for chemical, biochemical, and medical applications.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Thermodynamics
Tao Peng, Xiaodong Lin, Shuai Yuan, Mingyong Zhou, Bingyan Jiang, Yanwei Jia
Summary: This study demonstrated enhanced liquid mixing using ultrasonically activated attached bubbles in a microchannel. The bubbles were trapped in a hydrophobic surface microchannel and showed good stability. The results showed that reducing flow rate or increasing voltage improved mixing efficiency. The proposed chip allows for diverse mixing processes.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2023)
Article
Biotechnology & Applied Microbiology
Aoba Ota, Ayaka Mochizuki, Keitaro Sou, Shinji Takeoka
Summary: This paper investigates the potential of a static mixer (SM) in liposome formulation compared to a commonly used microfluidic device (SHM). The results indicate that liposomes prepared with SM have larger particle size but better size control, while liposomes prepared with SHM have higher encapsulation efficiency. Moreover, SM demonstrates significant advantages in user-friendliness, allowing for thorough cleaning of the mixing elements and device.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Analytical
Zhenghao Wang, Xingyang Yan, Qizhi Zhou, Qiaoyi Wang, Dongliang Zhao, Hongkai Wu
Summary: We reported a 3D PDMS micromixer based on the splitting-stretching-recombination (SSR) of streams, which can effectively and rapidly mix solutions with low Reynolds numbers. The micromixer is conveniently fabricated using two-photon polymerization (2PP) 3D printing and soft lithography, with high resolution, reproducibility, and ease of integration. It has better performance and higher chip miniaturization compared to other micromixers.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Chemical
Md Readul Mahmud, Shakhawat Hossain, Jin-Hyuk Kim
Summary: The numerical investigation of a new split and recombine (SAR) (Y - U)(beta) micromixer reveals that the maximum efficiency of 93% can be achieved when the connecting angle is 45 degrees. The study also covers the split and recombine process, the influence of secondary flow, pressure drop characteristics at various Reynolds numbers. Among all mixers examined, (Y - U)(45)degrees is found to be the best performing one.
Article
Engineering, Chemical
Tomasz Plusa, Jan Talaga, Andrzej Duda, Piotr Duda
Summary: This paper presents the results of measurements in uncovered baffled and unbaffled stirred tanks, using Laser Doppler Anemometry (LDA) to simulate mixing dynamics. Three turbulence models were verified and simulations were performed in both steady- and transient-state approaches. A simplified numerical model without the central vortex was proposed to reduce computational time, which can be used for designing and optimizing the mixing process.
Article
Biochemical Research Methods
Matteo Antognoli, Daniel Stoecklein, Chiara Galletti, Elisabetta Brunazzi, Dino Di Carlo
Summary: This study optimized mixing efficiency by analyzing sequences of cylindrical obstacles in the inertial regime, predicted and optimized interfacial stretching of co-flowing fluids using a specialized software, and tested new passive mixer designs using confocal microscopy and CFD simulations, achieving mixing efficiencies around 80%.
Article
Chemistry, Applied
Yunyan Guo, Jinqiang Zhou, Shujie Liu, Chongwei An, Jingyu Wang, Bidong Wu
Summary: Passive micromixers are commonly used in the preparation of ultrafine explosives due to their effective mixing and necessary safety. A novel passive micromixer was designed to produce nano-TATB and computational fluid dynamics (CFD) was used to simulate its mixing performance. The results demonstrate that the proposed micromixer exhibits good mixing performance at a Reynolds number range of 0.1 to 100, with a pressure drop of less than 28204 Pa at Re=100. A microfluidic recrystallization system was established and nano-TATB was successfully prepared using the new micromixer.
PROPELLANTS EXPLOSIVES PYROTECHNICS
(2023)
Article
Engineering, Chemical
Kiran Mathew Thomas, Baggie W. Nyande, Richard Lakerveld
Summary: This study evaluated the performance of a tubular crystallizer with gaps between the Kenics type mixing elements and compared it with a standard Kenics static mixer and a hollow tubular crystallizer. The gapped Kenics static mixer crystallizer showed advantages in terms of mixing length, shear rate, residence time distribution, pressure drop, and segregation or settling of crystals. Additionally, its crystallization performance, in terms of desupersaturation profile and mean crystal size, was similar to that of the standard Kenics static mixer crystallizer. The advantages of the gapped Kenics static mixer crystallizer, such as lower pressure drop and minimization of crystal settling, allow for lower flow rates and longer residence times under plug flow conditions, which is beneficial for continuous crystallization.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2022)
Article
Thermodynamics
E. Cetkin, A. F. Miguel
Summary: This study numerically analyzed the mixing efficiency and flow impedance in a spherical mixing chamber Y-shaped micromixer, identifying factors such as asymmetric ducts, angle, eccentricity, and inserted obstacles that affect mixing efficiency and flow impedance. The results showed that the volume of the spherical mixing chamber significantly impacts mixing efficiency and flow impedance.
JOURNAL OF APPLIED FLUID MECHANICS
(2021)
Article
Engineering, Chemical
Andrea Coletto, Pietro Poesio
Summary: Experiments and simulations were conducted to study the air volume fraction and hold-up in a bubble channel reactor. A new signal processing method was proposed to avoid the loss of bubble residence time. The results were in agreement with previous studies and a bubble-scale model was developed to explain the relationship between hold-up and air superficial velocity.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2024)
