Reprogramming axial ligands facilitates the self-assembly of a platinum(iv) prodrug: overcoming drug resistance and safer in vivo delivery of cisplatin

Light-Activatable Red Blood Cell Membrane-Camouflaged Dimeric Prodrug Nanoparticles for Synergistic Photodynamic/Chemotherapy

(2018) Qing Pei et al.   ACS Nano

Platinum(iv) prodrugs with long lipid chains for drug delivery and overcoming cisplatin resistance

(2018) Qiling Chen et al.   CHEMICAL COMMUNICATIONS

Triple action Pt(iv) derivatives of cisplatin: a new class of potent anticancer agents that overcome resistance

(2018) Emanuele Petruzzella et al.   Chemical Science

Paclitaxel dimers assembling nanomedicines for treatment of cervix carcinoma

(2017) Qing Pei et al.   JOURNAL OF CONTROLLED RELEASE

Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations

(2017) Hangxiang Wang et al.   Theranostics

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates

(2017) Vojtech Novohradsky et al.   Scientific Reports

Surfactant-Stripped Frozen Pheophytin Micelles for Multimodal Gut Imaging

(2016) Yumiao Zhang et al.   ADVANCED MATERIALS

Heterodinuclear Pt(iv)–Ru(ii) anticancer prodrugs to combat both drug resistance and tumor metastasis

(2016) Lili Ma et al.   CHEMICAL COMMUNICATIONS

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Lipid-based nanovesicles for nanomedicine

(2016) N. Grimaldi et al.   CHEMICAL SOCIETY REVIEWS

Redox-Hypersensitive Organic Nanoparticles for Selective Treatment of Cancer Cells

(2016) Wei Zhang et al.   CHEMISTRY OF MATERIALS

Platinum(iv) anticancer prodrugs – hypotheses and facts

(2016) Dan Gibson   DALTON TRANSACTIONS

Self-Assembled Redox Dual-Responsive Prodrug-Nanosystem Formed by Single Thioether-Bridged Paclitaxel-Fatty Acid Conjugate for Cancer Chemotherapy

(2016) Cong Luo et al.   NANO LETTERS

Self-Assembling Prodrugs by Precise Programming of Molecular Structures that Contribute Distinct Stability, Pharmacokinetics, and Antitumor Efficacy

(2015) Hangxiang Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Clinical Translation of Nanomedicine

(2015) Yuanzeng Min et al.   CHEMICAL REVIEWS

Structure-Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy

(2014) Hangxiang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin

(2014) Rakesh K. Pathak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells

(2014) Qinqin Cheng et al.   CHEMICAL COMMUNICATIONS

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Disulfide Bond Bridge Insertion Turns Hydrophobic Anticancer Prodrugs into Self-Assembled Nanomedicines

(2014) Yongjun Wang et al.   NANO LETTERS

Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines

(2014) Yumiao Zhang et al.   Nature Nanotechnology

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Synthetic Methods for the Preparation of Platinum Anticancer Complexes

(2013) Justin J. Wilson et al.   CHEMICAL REVIEWS

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity

(2012) P. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery

(2010) Youqing Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

(2010) N. Kolishetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA