4.7 Article

Epitope imprinted polyethersulfone beads by self-assembly for target protein capture from the plasma proteome

Journal

CHEMICAL COMMUNICATIONS
Volume 50, Issue 67, Pages 9521-9524

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc03428g

Keywords

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Funding

  1. National Basic Research Program of China [2012CB910601]
  2. National Nature Science Foundation [21375128, 21027002]
  3. Creative Research Group Project of the NSFC [21021004]
  4. National High Technology Research and Development Program of China [2012AA020202]

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Polymer self-assembly was developed as an epitope imprinting strategy involving facile processes and high recognition site density. As a model, transferrin epitope imprinted polyethersulfone (PES) beads were successfully fabricated using this technique. The imprinted beads demonstrated excellent selectivity toward the transferrin epitope and transferrin even in the real sample.

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