Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 10, Pages 1175-1177Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47581f
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Funding
- Wellcome Trust
- Biotechnology and Biological Sciences Research Council
- European Union
- Dulverton Trust
- Cancer Research UK
- BBSRC [BB/L000121/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/L000121/1] Funding Source: researchfish
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A convenient method for the synthesis of fluoromethylated carnitine biosynthesis intermediates, i.e. fluorinated derivatives of gamma-butyrobetaine and trimethyllysine, is described. The fluoromethylated probes were useful in both in vitro and cell based assays employing F-19 NMR and LC-MS analyses.
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