Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 18, Pages 2252-2254Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46903d
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Funding
- Australian Research Council (ARC)
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The first bifunctional Gd-III complexes covalently bound to arylphosphonium cations and the first tumour-cell selective mitochondrial agents designed for potential application in binary cancer therapies are reported. The highest in vitro cellular uptake for any Gd complex reported to date is described, with levels exceeding 10(10) Gd atoms per tumour cell.
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