A DNA-templated synthesis of encoded small molecules by DNA self-assembly

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA

(2014) Lourdes Encinas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

(2013) Reema K. Thalji et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3

(2013) Jeremy S. Disch et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multistep DNA-Templated Synthesis Using a Universal Template

(2013) Yizhou Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

20 years of DNA-encoded chemical libraries

(2011) Luca Mannocci et al.   CHEMICAL COMMUNICATIONS

Small-molecule discovery from DNA-encoded chemical libraries

(2011) Ralph E. Kleiner et al.   CHEMICAL SOCIETY REVIEWS

DNA-templated combinatorial assembly of small molecule fragments amenable to selection/amplification cycles

(2011) Jean Pierre Daguer et al.   Chemical Science

Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds

(2010) Fabian Buller et al.   ACS Chemical Biology

DNA as a Versatile Chemical Component for Catalysis, Encoding, and Stereocontrol

(2010) Scott K. Silverman   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selecting chemicals: the emerging utility of DNA-encoded libraries

(2010) Matthew A. Clark   CURRENT OPINION IN CHEMICAL BIOLOGY

In VitroSelection of a DNA-Templated Small-Molecule Library Reveals a Class of Macrocyclic Kinase Inhibitors

(2010) Ralph E. Kleiner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of TNF Inhibitors from a DNA-Encoded Chemical Library based on Diels-Alder Cycloaddition

(2009) Fabian Buller et al.   CHEMISTRY & BIOLOGY

A Yoctoliter-Scale DNA Reactor for Small-Molecule Evolution

(2009) Margit Haahr Hansen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

(2008) Fabian Buller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Translation of DNA into a Library of 13 000 Synthetic Small-Molecule Macrocycles Suitable forin VitroSelection

(2008) Brian N. Tse et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

(2008) L. Mannocci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA