Review
Chemistry, Organic
Camille Hauguel, Jean-Luc Pozzo, Abdallah Hamze, Olivier Provot
Summary: This review summarizes the recent advances in the synthesis of pyrrolo[3,2-b]indoles, indolo[3,2-b]indoles, and their polycyclic counterparts through novel strategies using metal or non-metal salts. The review includes examples of functionalized compounds and discusses the properties and reaction mechanisms of selected heterocycles.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Guang Chen, Xinyuan Cai, Xinying Zhang, Xuesen Fan
Summary: This paper presents a selective synthesis of indolo[1,2c]quinazolines and indolo[3,2-c]quinolines through cascade reactions. The approach involves the generation of a carbene species and its reaction with 2-(1H-indol-2-yl)aniline, followed by formation of a deoxygenative imine, intramolecular nucleophilic addition, and aromatization. The method provides a convenient access to polycyclic heteroaromatic compounds through direct C-H/N-H functionalization. The protocols offer advantages such as readily accessible substrates, tunable selectivity, good compatibility with diverse functional groups, and the use of air as a sustainable oxidant.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Xiu-Yu Chen, Hui Zheng, Ying Han, Jing Sun, Chao-Guo Yan
Summary: Functionalized isoquinolino[1,2-f][1,6]naphthyridines were obtained in good yields and with high dia-stereoselectivity through the three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature. Furthermore, the formal [2 + 2] cycloaddition reaction of dialkyl acetylenedicarboxylates and 5,6-unsubsti-tuted 1,4-dihydropyridines in refluxing acetonitrile gave unique 2-azabicyclo[4.2.0]octa-3,7-dienes as major products and 1,3a,4,6a-tetrahydrocyclopenta[b]pyrroles as minor products via further rearrangement.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Correction
Chemistry, Multidisciplinary
P. V. Santhini, V. Jayadev, Sourava C. Pradhan, Sivasankaran Lingamoorthy, P. R. Nitha, M. V. Chaithanya, Rakesh K. Mishra, Narayanan K. N. Unni, Jubi John, Suraj Soman
Summary: The study investigates the application of Indolo[3,2-b]indole donor-based D-pi-A dyes for dye-sensitized solar cells, revealing the crucial role of pi-spacers in recombination processes.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Optics
Sukanya Tongsuk, Ruttapol Malatong, Takdanai Unjarern, Chanikan Wongkaew, Panida Surawatanawong, Taweesak Sudyoadsuk, Vinich Promarak, Nopporn Ruangsupapichat
Summary: Considerable efforts have been devoted to improving fluorescent OLEDs using indolo[3,2-b]indole derivatives as electron donors. The new OLEDs demonstrated promising performance, indicating that these derivatives are potential candidates for OLED applications.
JOURNAL OF LUMINESCENCE
(2021)
Article
Chemistry, Organic
Xin-Wei Wang, Xiang Li, Mu-Wang Chen, Bo Wu, Yong-Gui Zhou
Summary: Chiral phosphoric acid-catalyzed Pictet-Spengler reactions have been successfully employed to synthesize a series of novel compounds with excellent yields and high enantiomeric excess.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Danman Guo, Yuyuan Wang, Jinzheng Chen, Yifeng Cao, Yiling Miao, Huahua Huang, Zhenguo Chi, Zhiyong Yang
Summary: A new organic room temperature phosphor, 1H-benzo[f]indole (Bd), has been discovered in this study. It has been confirmed that Bd can achieve ultralong room temperature phosphorescence not only when doped in carbazole derivatives, but also when doped in polymers with plenty of hydrogen bonds. This work is of great importance for the study of room temperature phosphorescence.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Applied
Deepa Rawat, Subbarayappa Adimurthy
Summary: The ruthenium-catalyzed reaction and the metal-free reaction proceed through different intermediates, indicating distinct mechanisms for the transformations. Control experiments suggest that both reactions follow the ionic mechanism.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Biochemistry & Molecular Biology
Fabiana Selos Guerra, Flaviana Rodrigues Fintelman Dias, Anna Claudia Cunha, Patricia Dias Fernandes
Summary: The new four benzo[f]indole-4,9-dione derivatives reduce TNBC cell viability by inducing ROS accumulation stress. These compounds exert cytotoxic effects on TNBC cells by activating caspase 9 and the Bax/Bcl-2 pathway through the intrinsic apoptosis pathway.
Article
Chemistry, Multidisciplinary
G. K. Sterligov, A. N. Lysenko, E. A. Drokin, L. I. Minaeva, M. A. Topchiy, A. A. Ageshina, S. A. Rzhevskiy, M. S. Nechaev, A. F. Asachenko
Summary: This article introduces a new easily scalable and solvent-free synthesis method for producing the important material chemistry compound "indolo[1,2-f]phenanthridine" from commercially available 6-chlorophenanthridine. The proposed method, which is catalyst-free and solvent-free, is more environmentally friendly and cost-effective compared to known methods.
RUSSIAN CHEMICAL BULLETIN
(2022)
Article
Chemistry, Organic
Azam Karimian, Zahra Karimi
Summary: In this study, a series of pyrimidothiazino-1,2,4-triazine derivatives were synthesized using a novel chemical reaction. The synthesized compounds were characterized and confirmed through spectroscopic and analytical data.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Khalid M. Abu Khadra, Huda A. AL-Saadi, Areej M. Assaf, Firas F. Awwadi, Shehadeh Mizyed
Summary: Synthesized benzoxazepine derivatives were characterized and evaluated using various analytical techniques. X-ray crystal structures of two compounds were obtained. The synthesized derivatives showed limited antimicrobial activity but displayed cytotoxicity against certain cancer cell lines and had varying effects on the release of pro-inflammatory cytokines. The study suggests that the derivatives have potential as anti-cancer and anti-inflammatory agents, depending on the type of cancer cell line.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Organic
Naser Sadeghpour Orang, Hadi Soltani, Mehdi Ghiamirad, Mehdi Ahmadi Sabegh
Summary: A new series of benzo[5,6]chromeno[3,2-c]quinoline derivatives were successfully synthesized with high yields using various arylglyoxal monohydrates, quinoline-2,4-dione, and beta-naphthol as reactants in a green solvent, under reflux conditions with p-toluenesulfonic acid as a mild catalyst. The structures of all new products were characterized using various analytical techniques.
HETEROCYCLIC COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Rayhaneh Alipoor, Mohammad Reza Mohammadizadeh, Dariush Saberi
Summary: This study reports the synthesis of two important families of organic compounds using one-pot three-component methods. The reactions were carried out using new starting materials and the products were identified using IR, H-1- and C-13-NMR spectra. The NMR spectra of some products showed asymmetric properties and the presence of diastereomers, as well as the formation of nonplanar eight-membered rings.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Organic
Ehsan Beyranvand, Bahador Karami, Mahnaz Farahi, Sedigheh Akrami
Summary: An impressive method for synthesizing benzo[5,6]chromeno[2,3-b]quinolin derivatives was described. The synthesis involves two steps: the synthesis of benzo[f]chromene-2-carbonitriles and the reaction with cyclohexanone to produce the desired derivatives in good to excellent yields under solvent-free conditions.
POLYCYCLIC AROMATIC COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Jinye Zhang, Shichang Luo, Yunlong Ma, Ruiyang Li, Yinghua Jin, Li Qiu, Wei Zhang
Summary: This study presents the fabrication method of cylindrical monolithic polyimine vitrimer/graphene composites with excellent mechanical, compressive, rehealable and recyclable, and piezoresistive properties. The composites exhibit outstanding durable compressibility, rapid recovery to the original size, high compressive strength, and high conductivity. The rehealing process achieves nearly 100% recovery of the compressive strength and electric conductivity under mild conditions, which is a desirable feature for electronic materials.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Rao Tao, Xin Zhao, Tianshu Zhao, Miaomiao Zhao, Ruiyang Li, Tianfu Yang, Lizhi Tang, Yinghua Jin, Wei Zhang, Li Qiu
Summary: In this proof-of-concept study, Imi-cage and Phos-cage organic molecular cages were designed to enhance emission through confinement effect. The cages exhibited higher fluorescence than free molecules in solid states, showcasing the potential for developing solid-state highly fluorescent materials. Additionally, Imi-cage showed promise for ultra-sensitive detection of explosives.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Review
Chemistry, Multidisciplinary
Rao Tao, Tianfu Yang, Yan Wang, Jingmin Zhang, Zhengyi Wu, Li Qiu
Summary: Supercapacitors (SCs) are considered a promising electrochemical energy storage (EES) device due to their high-power density, longer lifespan, faster charge and discharge capabilities, and environmental friendliness. Covalent organic frameworks (COFs), a newly emerging class of crystalline porous polymeric materials, have been found to have significant potential for application in EES devices due to their unique properties such as atomically adjustable structures, robust and tunable skeletons, well-defined and open channels, and high surface areas. This feature article aims to summarize the design strategies of COF-based electrode materials for SCs based on representative advances, as well as highlighting the current challenges and future perspectives of COFs for SC application.
CHEMICAL COMMUNICATIONS
(2023)
Article
Materials Science, Multidisciplinary
Bowen Li, Xiangyu Zou, Qiyi Li, Hongqian Sang, Youbing Mu, Jieyu Wang, Jian Pei, Chunming Yang, Liang Li, Xiaobo Wan
Summary: Research on conjugated polymers with planar backbone has led to the development of high charge carrier mobility in organic filed-effect transistors (OFETs). Two new ambipolar polymers with the same backbone but with/without hexyl sidechains were synthesized and their charge transport properties were compared. The results showed that the polymer with a moderately twisted backbone due to the sidechain exhibited higher crystallinity, smoother surface morphology, and better charge transport, suggesting the importance of considering the backbone geometry in the design of high-performance OFETs.
ORGANIC ELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Zihan Xiong, Wei Wen, Yifei Zhu, Youbing Mu, Zhiyuan Zhao, Zhenggang Lan, Xiaobo Wan, Yunqi Liu
Summary: This study reports the synthesis of two methoxylated isoindigo molecules and investigates the charge transport behaviors of their copolymers with bisthiophene (2T) and bisthiazole (2Tz). The position of substitution has a drastic influence on the UV-vis absorption and electrochemical properties of both monomers and polymers. The presence of O center dot center dot center dot S conformation lock is confirmed by theoretical calculations and single crystal structure analysis, but the methoxy substitutions also change the aggregation behaviors of the corresponding polymers, which has a negative effect on charge transport. Among the four polymers, the one consisting of 5,5'-methoxylated isoindigo and 2T shows the best hole mobility of 1.9 x 10(-1) cm(2) V-1 s(-1).
MACROMOLECULAR MATERIALS AND ENGINEERING
(2023)
Article
Polymer Science
Shiwei Duan, Zhedong Li, Yuetao Liu, Na Zhao, Zhibo Li
Summary: This study reports a facile method to prepare diphenyl silicone elastomer precursors with controlled structure by cyclic trimeric phosphazene base (CTPB) catalyzed ring -opening copolymerization. The resulting silicone elastomers exhibit excellent elasticity and thermal aging resistance, making them versatile for various applications.
Article
Polymer Science
Zhedong Li, Shiwei Duan, Na Zhao, Zhibo Li
Summary: In this study, two bulky phenyl diphosphazene bases, p-PDPB and m-PDPB, were synthesized and used in combination with ureas and squaramides as hydrogen-bond donors to mediate stereocontrolled ring opening polymerization (ROP) of lactide. The phenyl diphosphazene based/urea binary catalytic system successfully synthesized semicrystalline PLAs with narrow dispersity and high tacticity (P-m up to 0.84) in a well-controlled manner. Structural analysis confirmed the linear structure and high end-group fidelity of the resulting polymers, and MALDI-TOF MS analysis indicated the good controllability of the binary catalytic system with minimal transesterification.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Chemistry, Physical
Juanjuan Zhang, Jiawei Peng, Yifei Zhu, Deping Hu, Zhenggang Lan
Summary: The impact of mode-specific vibrational excitations on initial-preparation conditions in nonadiabatic dynamics of methyl nitrate was investigated. Exciting specific modes with a single quantum of energy resulted in slower population decay rates. This study provides insights into the key mechanisms of nonadiabatic dynamics control and demonstrates the potential for controlling nonadiabatic dynamics through mode-specific vibrational excitations.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Materials Science, Multidisciplinary
Ruiyang Li, Yunlong Ma, Tianfu Yang, Xiaoran Yang, Rao Tao, Yinghua Jin, Wei Zhang, Li Qiu
Summary: Incorporating an aggregation-induced emission (AIE) effect into polymers can create AIE-active polymers that have great potential in optoelectronics and sensing applications. This study successfully prepared a series of AIE-active polyimine vitrimers (TPE-PIs) by integrating AIE-active monomers into the polymer network. The TPE-PIs not only inherit the merits of PI vitrimers but also provide enhanced mechanical and luminescent properties compared to other AIE-active and AIE-inactive polymers. The possibility of significantly enhancing their photoluminescence intensity in an underwater environment makes them useful for underwater sensing and light-emitting applications.
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Physical
Jianzheng Ma, Di Zhao, Le Yu, Chenwei Jiang, Zhenggang Lan, Fuli Li
Summary: We theoretically designed a highly efficient light-driven molecular rotary motor using electronic structure calculations and nonadiabatic dynamics simulations, which showed excellent performance in both photo- and thermal isomerization processes. By modifying the structure of a synthesized compound, we proposed an oxindole-based light-driven molecular rotary motor with significant electronic push-pull character and weak steric hindrance. The newly designed motor displayed improved quantum yield and different motion behavior compared to the original motor, suggesting the feasibility of enhancing the efficiencies of photo- and thermal isomerization in molecular motors.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Physical
Yutai Zhang, Chao Xu, Zhenggang Lan
Summary: We developed an automated approach to construct complex reaction networks and explore reaction mechanisms by integrating various theoretical methods. This method combines nanoreactor-type molecular dynamics, metadynamics, semiempirical GFN2-xTB method, and hidden Markov model. It provides an efficient and accurate tool for the automated exploration of reaction networks.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION
(2023)
Article
Chemistry, Physical
Rao Tao, Tianfu Yang, Xian Li, Haofeng Gao, Shuangbin Liu, Yan Wang, Mingquan Yuan, Li Qiu
Summary: In this study, an organic molecular cage based on SbPh3 was synthesized and used to mediate the growth of palladium nanoparticles. The resulting ultrafine PdNPs showed good catalytic activity and stability in the reaction.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Applied
Rao Tao, Yaqian Zheng, Yan Wang, Tianfu Yang, Li Qiu
Summary: A series of covalent triazine-based frameworks (CTFs) were prepared by ionothermal synthesis and rearrangement, and CTF-immobilized nano-Pd(0) catalysts with different particle size distributions were successfully prepared using suspension impregnation-in-situ reduction. Among them, the smallest and highly dispersed Pd nanoclusters showed excellent activity and recyclability. This study provides new insights for the preparation of high-performance metal nano-catalysts.
MICROPOROUS AND MESOPOROUS MATERIALS
(2023)
Article
Chemistry, Physical
Yifei Zhu, Jiawei Peng, Xu Kang, Chao Xu, Zhenggang Lan
Summary: The analysis protocol proposed in this paper provides a powerful way to clarify both the major and minor active molecular motions of the ring distortion in nonadiabatic dynamics, using dimensionality reduction and clustering approaches. The representative system keto isocytosine is used to illustrate the protocol.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Materials Science, Biomaterials
Chenxi Xiong, Wenjuan Xiong, Youbing Mu, Danfeng Pei, Xiaobo Wan
Summary: Block copolymers with different topologies were synthesized to form a robust antifouling nanolayer, among which the 4-armed copolymer exhibited the best antifouling efficiency and superhydrophilic surface, along with excellent cytocompatibility.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
