Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 55, Pages 7367-7370Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc02947j
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Funding
- National Natural Science Foundation of China [21372017, 21290183]
- National Basic Research Program of China (973 Program) [2010CB833200]
- PhD Programs Foundation of Ministry of Education of China [20120001110100]
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The rhodium(III)-catalyzed intramolecular annulation of alkyne-tethered acetanilides for the synthesis of fused tricyclic indole scaffolds via C-H activation has been developed, which has the potential for the synthesis of many indole alkaloids. This reaction proceeds under mild reaction conditions and with tolerance to a variety of functional groups.
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