Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 4, Pages 445-447Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc47841f
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- University of Bologna (RFO)
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Indoles bearing Michael acceptors at the 4-position were engaged in organocatalytic enantioselective cascade reactions with enals. Careful optimisation of the reaction parameters overcame the inherent low reactivity of these substrates, rendering 3,4-ring fused indoles in good yields, excellent enantioselectivities and as single diastereoisomers.
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