A genetically encoded aldehyde for rapid protein labelling

Genetic Incorporation of Seven ortho-Substituted Phenylalanine Derivatives

(2014) Jeffery M. Tharp et al.   ACS Chemical Biology

The genetic incorporation of thirteen novel non-canonical amino acids

(2014) Alfred Tuley et al.   CHEMICAL COMMUNICATIONS

A Genetically Encoded Acrylamide Functionality

(2013) Yan-Jiun Lee et al.   ACS Chemical Biology

Well-Defined Aminooxy Terminated N-(2-Hydroxypropyl) Methacrylamide Macromers for Site Specific Bioconjugation of Glycoproteins

(2013) Pradeep K. Dhal et al.   BIOCONJUGATE CHEMISTRY

α-Oxo Aldehyde or Glyoxylyl Group Chemistry in Peptide Bioconjugation

(2013) Ouafâa El-Mahdi et al.   BIOCONJUGATE CHEMISTRY

Hydrazino-Pictet-Spengler Ligation as a Biocompatible Method for the Generation of Stable Protein Conjugates

(2013) Paresh Agarwal et al.   BIOCONJUGATE CHEMISTRY

Enhanced Catalysis of Oxime-Based Bioconjugations by Substituted Anilines

(2013) Michaela Wendeler et al.   BIOCONJUGATE CHEMISTRY

Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor

(2013) Shujiang Wang et al.   BIOMACROMOLECULES

The nitrilimine–alkene cycloaddition is an ultra rapid click reaction

(2013) Xiaoshan Shayna Wang et al.   CHEMICAL COMMUNICATIONS

Site-Specific Protein Transamination Using N-Methylpyridinium-4-carboxaldehyde

(2013) Leah S. Witus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Chemoselective Assembly of Hyaluronic Acid Networks and Nanogels for Drug Delivery

(2013) Dmitri Ossipov et al.   MACROMOLECULES

Development of bis-unsaturated ester aldehydes as amino-glue probes: sequential double azaelectrocyclization as a promising strategy for bioconjugation

(2013) Katsunori Tanaka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Genetic Incorporation of Twelve meta-Substituted Phenylalanine Derivatives Using a Single Pyrrolysyl-tRNA Synthetase Mutant

(2012) Yane-Shih Wang et al.   ACS Chemical Biology

Amino Acids for Diels-Alder Reactions in Living Cells

(2012) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorescence Quenchers for Hydrazone and Oxime Orthogonal Bioconjugation

(2012) Pete Crisalli et al.   BIOCONJUGATE CHEMISTRY

Catalyst-Free and Site-Specific One-Pot Dual-Labeling of a Protein Directed by Two Genetically Incorporated Noncanonical Amino Acids

(2012) Bo Wu et al.   CHEMBIOCHEM

Genetic Encoding of a Bicyclo[6.1.0]nonyne-Charged Amino Acid Enables Fast Cellular Protein Imaging by Metal-Free Ligation

(2012) Annika Borrmann et al.   CHEMBIOCHEM

Site-Specific Protein Modification Using Lipoic Acid Ligase and Bis-Aryl Hydrazone Formation

(2012) Justin D. Cohen et al.   CHEMBIOCHEM

Residue choice defines efficiency and influence of bioorthogonal protein modification via genetically encoded strain promoted Click chemistry

(2012) Samuel C. Reddington et al.   CHEMICAL COMMUNICATIONS

Enabling Wittig reaction on site-specific protein modification

(2012) Ming-Jie Han et al.   CHEMICAL COMMUNICATIONS

Synthesis of Aldehyde-Linked Nucleotides and DNA and Their Bioconjugations with Lysine and Peptides through Reductive Amination

(2012) Veronika Raindlová et al.   CHEMISTRY-A EUROPEAN JOURNAL

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

(2012) Kathrin Lang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Rationally Designed Pyrrolysyl-tRNA Synthetase Mutant with a Broad Substrate Spectrum

(2012) Yane-Shih Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Pictet-Spengler ligation for protein chemical modification

(2012) P. Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aromatic Aldehyde and Hydrazine Activated Peptide Coated Quantum Dots for Easy Bioconjugation and Live Cell Imaging

(2011) Gopal Iyer et al.   BIOCONJUGATE CHEMISTRY

Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag

(2011) Jason E. Hudak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of l-phenylalanine and its derivatives

(2011) Yane-Shih Wang et al.   Molecular BioSystems

Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions

(2010) Dmitri A. Ossipov et al.   CHEMICAL COMMUNICATIONS

Efficient Bioconjugation of Protein Capture Agents to Biosensor Surfaces Using Aniline-Catalyzed Hydrazone Ligation

(2010) Ji-Yeon Byeon et al.   LANGMUIR

Synthesis of peptide macrocycles using unprotected amino aldehydes

(2010) Benjamin H Rotstein et al.   Nature Protocols

Direct Polymerase Synthesis of Reactive Aldehyde-Functionalized DNA and Its Conjugation and Staining with Hydrazines

(2009) Veronika Raindlová et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications

(2009) Ying Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High-efficiency labeling of sialylated glycoproteins on living cells

(2009) Ying Zeng et al.   NATURE METHODS

Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag

(2009) P. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Oxime and Hydrazone Ligations with Aromatic Aldehydes for Biomolecular Labeling

(2008) Anouk Dirksen et al.   BIOCONJUGATE CHEMISTRY

Synthesis and bioorthogonal coupling chemistry of a novel cyclopentenone-containing unnatural tyrosine analogue

(2008) Gianni R. Lorello et al.   BIOORGANIC CHEMISTRY

Characterization of a Three-Component Coupling Reaction on Proteins by Isotopic Labeling and Nuclear Magnetic Resonance Spectroscopy

(2008) Jesse M. McFarland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymesin Vitroandin Vivo

(2008) Jason S. Rush et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY