Journal
CHEMICAL COMMUNICATIONS
Volume 50, Issue 38, Pages 4908-4910Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc01692k
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- National Science Foundation [CHE-1149327]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1149327] Funding Source: National Science Foundation
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A 15-step synthesis of the iGluR antagonist kaitocephalin from aspartic acid is reported. The linchpin pyrrolidine ring of the target molecule is efficiently assembled with in a single operation via an asymmetric [C+NC+CC] reaction.
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