An efficient route to chiral N-heterocycles bearing a C–F stereogenic center via asymmetric hydrogenation of fluorinated isoquinolines

Copper-Catalyzed Hydrodefluorination of Fluoroarenes by Copper Hydride Intermediates

(2013) Hongbin Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Fluorinated Building Blocks by Transition-Metal-Mediated Hydrodefluorination Reactions

(2013) Moritz F. Kuehnel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Iridium-Catalyzed Hydrogenation of 1- and 3-Substituted Isoquinolinium Salts

(2013) Zhi-Shi Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation of Isoquinolinium Salts Catalyzed by Chiral Iridium Complexes: Direct Synthesis for Optically Active 1,2,3,4-Tetrahydroisoquinolines

(2013) Atsuhiro Iimuro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Anion Phase-Transfer Catalysis Applied to the Direct Enantioselective Fluorinative Dearomatization of Phenols

(2013) Robert J. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Iridium-Catalyzed Hydrogenation of 3,4-Disubstituted Isoquinolines

(2012) Lei Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Diastereo- and Enantioselective Organocatalytic One-Pot Sequential 1,4-Addition/Dearomative-Fluorination Transformation

(2012) Feng Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric One-Pot Sequential Conjugate Addition/Dearomative Fluorination: Synthesis of Chiral Fluorinated Isoxazol-5(4H)-ones

(2012) Wen-Ting Meng et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Fluorination of Enamides: Access to α-Fluoroimines Using an Anionic Chiral Phase-Transfer Catalyst

(2012) Robert J. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ag(I)-Catalyzed Aminofluorination of Alkynes: Efficient Synthesis of 4-Fluoroisoquinolines and 4-Fluoropyrrolo[α]isoquinolines

(2012) Tao Xu et al.   ORGANIC LETTERS

C−F and C−H Bond Activation of Fluorobenzenes and Fluoropyridines at Transition Metal Centers: How Fluorine Tips the Scales

(2011) Eric Clot et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Hydrodefluorination of Pentafluorobenzene by [Ru(NHC)(PPh3)2(CO)H2]: A Nucleophilic Attack by a Metal-Bound Hydride Ligand Explains an Unusual ortho-Regioselectivity

(2011) Julien A. Panetier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Hydrogenation of Heteroarenes and Arenes

(2011) Duo-Sheng Wang et al.   CHEMICAL REVIEWS

Highly Enantioselective Partial Hydrogenation of Simple Pyrroles: A Facile Access to Chiral 1-Pyrrolines

(2011) Duo-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Asymmetric Electrophilic Fluorination Using an Anionic Chiral Phase-Transfer Catalyst

(2011) V. Rauniyar et al.   SCIENCE

Dehydration triggered asymmetric hydrogenation of 3-(α-hydroxyalkyl)indoles

(2011) Duo-Sheng Wang et al.   Chemical Science

Highlights of Transition Metal-Catalyzed Asymmetric Hydrogenation of Imines

(2010) Nicolas Fleury-Brégeot et al.   ChemCatChem

Highly Efficient Iridium-Catalyzed Asymmetric Hydrogenation of Unprotected β-Enamine Esters

(2010) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium−Monodentate Phosphoramidite-Catalyzed Asymmetric Hydrogenation of Substituted Benzophenone N−H Imines

(2010) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Asymmetric Hydrogenation of Unprotected Indoles Activated by Brønsted Acids

(2010) Duo-Sheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Selective Iridium-Catalyzed Asymmetric Hydrogenation of Trifluoromethyl Olefins: A New Route to Trifluoromethyl- Bearing Stereocenters

(2009) Mattias Engman et al.   ADVANCED SYNTHESIS & CATALYSIS

C−F Bond Activation in Organic Synthesis

(2009) Hideki Amii et al.   CHEMICAL REVIEWS

Fluorine & chirality: how to create a nonracemic stereogenic carbon–fluorine centre?

(2009) Dominique Cahard et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Hydrogenation of N−H Imines

(2009) Guohua Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective synthesis of a chiral fluoropiperidine via asymmetric hydrogenation of a vinyl fluoride

(2009) Shane W. Krska et al.   TETRAHEDRON

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Asymmetric Fluorination Comes of Age

(2007) Vincent A. Brunet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS