4.7 Article

Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 9, Pages 907-909

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37517f

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Funding

  1. University of Maryland [70NANB10H193]
  2. National Institute of Standards and Technology Center for Nanoscale Science and Technology through the University of Maryland [70NANB10H193]

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The binding process of quantum dots and DNA origami was monitored using a 3D, real-time, single-particle tracking system. Single-molecule binding events were directly observed and precise measurements of the diffusion coefficient and second-order photon correlation function, g(2)(tau), were combined to distinguish free quantum dots from different conjugates of nQdot-origami.

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