4.7 Article

An ultrasensitive aptameric sensor for proteins based on hyperbranched rolling circle amplification

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 86, Pages 10115-10117

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc45521a

Keywords

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Funding

  1. NSFC [21305014, 21275031, 81202912, 21175024, 41076059, 20905013]
  2. Natural Science Foundation of Fujian Province [2011J01035]
  3. Developmental Fund of Chen Keji Integrative Medicine [CKJ20110003]
  4. Key Subject of Ecology, Fujian Province [6112C0600]
  5. Program for Changjiang Scholars and Innovative Research Team in University [IRT1116]

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A novel fluorescent aptameric sensor for thrombin has been developed by combination of the high amplification efficiency of HRCA and the specific function of aptameric recognition.

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