Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 85, Pages 10022-10024Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46070c
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Funding
- University of Warwick
- EPSRC
- European Regional Development Fund
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Amino-amides are important pharmaceutical building-blocks. The enantioselective reduction of trichloromethyl ketones using ruthenium transfer hydrogenation catalysts is reported. The products react in a range of Jocic-type reactions to give enantiomerically enriched amino-amides.
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