Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 42, Pages 4758-4760Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc40868j
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Funding
- Nanyang Assistant Professor Fellowship [M4080531]
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A new G-quadruplex (GQ) stabilizer, [Pt(Dip)(2)](PF6)(2) (Dip: 4,7-diphenyl-1,10-phenanthroline), is prepared by the microwave irradiation method. The complex can highly stabilize G-quadruplex, but has negligible interactions with duplex DNA. Aromatic anchors on the polypyridyl ligands bestow the stabilizer with a high binding preference towards parallel GQ.
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