Article
Biochemistry & Molecular Biology
Clement Kotras, Maxime Leclercq, Maxime Roger, Camille Bouillon, Antonio Recupido, Aurelien Lebrun, Yannick Bessin, Philippe Gerbier, Sebastien Richeter, Sebastien Ulrich, Sebastien Clement, Mathieu Surin
Summary: Dynamic covalent polymers (DCPs) that combine cationic units and fluorescent units show promise in the recognition and delivery of nucleic acids. The design of acylhydrazone-based DCPs with cationic arginine units and pi-conjugated fluorescent moieties is explored, and the (chir)optical properties of the DCPs and their complexes with various DNA types are investigated.
Article
Chemistry, Multidisciplinary
Hai-Ning Zhang, Hui-Jun Feng, Yue-Jian Lin, Guo-Xin Jin
Summary: By utilizing multiple stacking interactions between components, two kinds of metalla-links with molecular Borromean rings (6(2)(3) links) and head-to-tail cyclic [3]catenanes (6(1)(3) links) were successfully synthesized in high yield using tri-mu-methoxyl-dinuclear complexes as unusual cationic guests during coordination-driven assembly. The topology of these intricate structures was controlled by strategically selecting different dipyridyl ligands, as confirmed by X-ray crystallography and mass spectrometry analysis. The behavior of these metalla-links in solution was further studied using NMR techniques.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Physics, Multidisciplinary
Joachim H. Rosenberger, Tobias Goeppel, Patrick W. Kudella, Dieter Braun, Ulrich Gerland, Bernhard Altaner
Summary: Research has revealed the existence of two distinct length scales in the self-assembly of complex informational polymers from prebiotic building blocks, representing the onset of a strongly nonequilibrium regime and a local concentration maximum. This finding helps to understand the role of structure-forming processes in the early stages of prebiotic evolution.
Article
Chemistry, Multidisciplinary
Ya-Liang Lai, Hao-Jie Zhang, Juan Su, Xue-Zhi Wang, Dong Luo, Jia-Xing Liu, Xiao-Ping Zhou, Dan Li
Summary: In this study, a covalent cage TPE-Zn4 based on a tetraphenylethylene molecule was reported, which was templated by zinc ions via subcomponent self-assembly. TPE-Zn4 exhibited a quadrangular prismatic cage structure characterized by NMR, mass spectrum, and single-crystal X-ray diffractions. TPE-Zn4 emitted orange fluorescence (λem = 620 nm) in DMSO solution under UV light irradiation (λex = 395 nm), and it could be used as a fluorescence sensor for selectively detecting Pd2+. The fluorescence of TPE-Zn4 was quenched by Pd2+ in DMSO solution, achieving a very low detection limit of 62.3 nM. Mechanism studies revealed that the fluorescence quenching was probably caused by the replacement of Zn2+ by Pd2+, as well as the heavy atom effect and chelation-enhanced quenching effect between Pd2+ and the cage.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Alessandro Marchetti, Alessandro Gori, Anna Maria Ferretti, Daniel Arenas Esteban, Sara Bals, Claudia Pigliacelli, Pierangelo Metrangolo
Summary: Finite 3D structures with controlled morphology can be achieved in the out-of-equilibrium self-assembly of Au NPs using a spherical peptide-gold superstructure (PAuSS) as a template, resulting in a transient 3D-branched Au-nanoshell (BAuNS) stabilized by sodium dodecyl sulphate (SDS). The BAuNS dismantles and regresses to PAuSS through equilibrium of SDS concentration gradient over time in the sample solution, causing NP disassembly. The assembly and disassembly of BAuNS promote temporary interparticle plasmonic coupling, enabling reversible and tunable changes in their plasmonic properties, which is highly desirable for the development of optoelectronic nanodevices.
Review
Chemistry, Multidisciplinary
Mostafa A. Elbahnasawy, Mahmoud L. Nasr
Summary: Lipid-bilayer nanodiscs and liposomes are used to stabilize membrane proteins and study their structures and functions. DNA-origami nanostructures can be used as templates to control the shapes and arrangements of lipid bilayers, which is crucial for the study of large membrane proteins.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Xiao Wang, Ruojie Sha, William B. Knowlton, Nadrian C. Seeman, James W. Canary, Bernard Yurke
Summary: A chiral dimer of an organic semiconductor was created by assembling an octamer of polyaniline with DNA. The dimer showed easy reconfiguration between its monomeric and dimeric forms. Experimental and theoretical studies were conducted to examine the dimer's geometry and the exciton coupling between its molecules. Protonic doping allowed for easy switching between different electronic states, and the dimer exhibited a Davydov splitting similar to DNA-dye systems with strong transition dipoles. This research provides a possible platform for studying the fundamental properties of organic semiconductors with DNAtemplated assemblies, which have potential applications in artificial light-harvesting systems and excitonic devices.
Article
Chemistry, Multidisciplinary
Sofia Julin, Nonappa, Boxuan Shen, Veikko Linko, Mauri A. Kostiainen
Summary: Lipids play a crucial role in cellular compartments, and co-assembly of DNA origami with cationic lipids enhances the order and stability of lipid structures. This complexation strategy effectively protects DNA origami against nuclease digestion, opening up new possibilities for the construction of cell-membrane-associated components.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Selina Hollstein, Oleksandr Shyshov, Marko Hanzevacki, Jie Zhao, Tamara Rudolf, Christof M. Jaeger, Max von Delius
Summary: This study reports on the dynamic covalent self-assembly of anion cryptates that offer an inherent mechanism for the release of guest ions. These self-assembled architectures exhibit moderate affinity for anions such as chloride, bromide or iodide, making them suitable for membrane transport applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Dong Hwan Kim, Hong Gu Kwon, Hong Kyoon Choi
Summary: In this study, dewetting-induced hierarchical patterns were successfully formed using two self-assembled materials: block copolymers and colloidal crystals. The periodic structures of colloidal crystals were used as templates to generate multi-scale hierarchical patterns with block copolymers. Various concentric ring patterns were observed and explained using a free energy model. Spiral-defective features were also examined and found to be promoted by Y-junction defects.
Article
Chemistry, Multidisciplinary
Kathryn N. Guye, Hao Shen, Muammer Y. Yaman, Gerald Y. Liao, David Baker, David S. Ginger
Summary: The study focuses on the protein-directed assembly of colloidal gold nanoparticles on de novo designed protein nanofiber templates. By controlling the size of nanoparticles and the pH of the solution, the importance of charge-dependent particle-fiber and particle-substrate interactions is explored. A negative correlation between particle size and attachment density to protein nanofibers is found, with pH-dependent particle attachment density and binding specificity observed. Hyperspectral scattering microscopy is used to draw conclusions about particle density and interparticle spacings of optically observable particle assemblies.
Article
Chemistry, Multidisciplinary
Henry J. Shulevitz, Tzu-Yung Huang, Jun Xu, Steven J. Neuhaus, Raj N. Patel, Yun Chang Choi, Lee C. Bassett, Cherie R. Kagan
Summary: In this study, a scalable strategy using capillary-driven, template-assisted self-assembly is presented to form ordered arrays of nanodiamonds. Measurements of over 200 nanodiamonds reveal a statistical understanding of their structural, optical, and quantum properties.
Article
Spectroscopy
Lingyuan Liu, Qianyi Zhang, Feng Li, Mei Wang, Jing Sun, Shuyun Zhu
Summary: Fluorescent DNA-templated silver nanoclusters were synthesized and used as a novel probe for detecting D-penicillamine for the first time, showing high sensitivity and fast preparation process.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Multidisciplinary
Yuxiang Dong, Jiliang Liu, Xuanzhao Lu, Jialin Duan, Liqi Zhou, Lizhi Dai, Min Ji, Ningning Ma, Yong Wang, Peng Wang, Jun-Jie Zhu, Qianhao Min, Oleg Gang, Ye Tian
Summary: Self-assembly processes are important for fabricating complexly organized nanomaterials, but often limited in creating structures with multiscale order. In this study, a two-stage assembly strategy is introduced to successfully form complexly organized nanoparticle crystals.
Article
Chemistry, Analytical
Pinky Chowdhury, Seokjoon Kim, Eun Sung Lee, Byung Seok Cha, Ki Soo Park
Summary: This study demonstrates the rational design of DNA oligonucleotides that form self-assembled micelles and generate high fluorescence signals when combined with CuNCs. By attaching a specific DNA aptamer to the micelles, selectivity towards target cancer cells is achieved.
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)