4.7 Article

Development of a signal-on electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 33, Pages 3422-3424

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc41281d

Keywords

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Funding

  1. Nebraska EPSCoR [EPS-1004094]
  2. NSF [CHE-0955439]
  3. Direct For Mathematical & Physical Scien
  4. Division Of Chemistry [0955439] Funding Source: National Science Foundation
  5. Office Of The Director
  6. EPSCoR [1004094] Funding Source: National Science Foundation

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We report a reagentless and reusable signal-on electrochemical DNA sensor that utilizes oligo-thymine as a flexible spacer. This sensor design is sensitive, specific, and selective; it is potentially generalizable for detection of a wide range of biomedical-relevant nucleic acid sequences.

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