Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors

A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin

(2010) Sungwook Choi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

(2010) Stephen Connelly et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Substructure Combination Strategy To Create Potent and Selective Transthyretin Kinetic Stabilizers That Prevent Amyloidogenesis and Cytotoxicity

(2010) Sungwook Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Stilbene That Binds Selectively to Transthyretin in Cells and Remains Dark until It Undergoes a Chemoselective Reaction To Create a Bright Blue Fluorescent Conjugate

(2010) Sungwook Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Repertoire of Fluorescent Calcium Sensors

(2009) Amy E. Palmer   ACS Chemical Biology

Constructing and Exploiting the Fluorescent Protein Paintbox (Nobel Lecture)

(2009) Roger Y. Tsien   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward Optimization of the Second Aryl Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies†

(2009) Steven M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Use of Coumarins as Environmentally-Sensitive Fluorescent Probes of Heterogeneous Inclusion Systems

(2009) Brian Wagner   MOLECULES

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Fluorescent biosensors of protein function

(2008) Schuyler B VanEngelenburg et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Toward Optimization of the Linker Substructure Common to Transthyretin Amyloidogenesis Inhibitors Using Biochemical and Structural Studies†

(2008) Steven M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorescent probes for super-resolution imaging in living cells

(2008) Marta Fernández-Suárez et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors

(2007) Steven M. Johnson et al.   JOURNAL OF MEDICINAL CHEMISTRY