Journal
CHEMICAL COMMUNICATIONS
Volume 49, Issue 98, Pages 11491-11493Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc46695g
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Funding
- Ministerio de Ciencia e Innovacion [CTQ2009-08810]
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The mono-[F-18] fluorination of o-carborane via nucleophilic substitution is reported. The new radiochemical transformation uses cyclotron produced [F-18]F- and a carboranyl iodonium salt. Further derivatization of the F-18-labelled carborane is achieved by formation of the C-c-lithio salt and reaction with an aldehyde.
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