Short, terminally modified 2′-OMe RNAs as inhibitors of microRNA

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors

(2012) Jun Xie et al.   NATURE METHODS

A potent 2′ -O- methylated RNA-based microRNA inhibitor with unique secondary structures

(2012) Takeshi Haraguchi et al.   NUCLEIC ACIDS RESEARCH

A 5′-Cap for DNA Probes Binding RNA Target Strands

(2011) Simone Egetenmeyer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemical modification and design of anti-miRNA oligonucleotides

(2011) K A Lennox et al.   GENE THERAPY

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

The prognostic and functional role of microRNAs in acute myeloid leukemia

(2010) G. Marcucci et al.   BLOOD

MiRNA activity directs stem cell commitment to a particular fate

(2010) Eran Hornstein   CELL CYCLE

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

(2010) Ellen Marie Straarup et al.   NUCLEIC ACIDS RESEARCH

A Locked Nucleic Acid Antisense Oligonucleotide (LNA) Silences PCSK9 and Enhances LDLR Expression In Vitro and In Vivo

(2010) Nidhi Gupta et al.   PLoS One

miRNA-based mechanism for the commitment of multipotent progenitors to a single cellular fate

(2010) M. Mann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A short antisense oligonucleotide masking a unique intronic motif prevents skipping of a critical exon in spinal muscular atrophy

(2010) Natalia N. Singh et al.   RNA Biology

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

(2009) Jesper Worm et al.   NUCLEIC ACIDS RESEARCH

Down-Regulation of miR-92 in Human Plasma Is a Novel Marker for Acute Leukemia Patients

(2009) Masami Tanaka et al.   PLoS One

Short Antisense Oligonucleotides with Novel 2′−4′ Conformationaly Restricted Nucleoside Analogues Show Improved Potency without Increased Toxicity in Animals

(2008) Punit P. Seth et al.   JOURNAL OF MEDICINAL CHEMISTRY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE