Review
Chemistry, Inorganic & Nuclear
Praveen Kumar Singh, Poulomi Majumdar, Surya Prakash Singh
Summary: PPGs are beneficial tools for controlled release of bioagents, and visible/NIR light activated BODIPY PPGs with tunable spectral properties and low phototoxicity are effective for releasing protecting groups.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Albert M. Schulte, Georgios Alachouzos, Wiktor Szymanski, Ben L. Feringa
Summary: The study presents a novel approach to significantly increase the photolysis quantum yield (QY) of heterolytic PPGs by stabilizing an intermediate chromophore cation. This strategy is applicable to different photolysis payloads and even different classes of PPGs, providing valuable insights into the factors determining photolysis efficiency.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Hongpeng Yang, Lei Chen, Shouguo Zhang, Gang Wang, Tingting Chen, Jing Xu, Tao Peng, Lin Wang, Liming Hu
Summary: In this study, we have successfully designed and synthesized a photolabile protecting group (PLPG) that can rapidly release thiol groups within a short period of time. The photolytic reaction is mild and does not involve acid cleavage, resulting in good yields and no side reactions as confirmed by HPLC analysis.
Article
Polymer Science
Jungyeon Kim, Valentin Beyer, C. Remzi Becer
Summary: In this study, we have developed a simple and elegant approach for the synthesis of poly(2-oxazoline) (POx) with pendant hydroxyl groups, using silyl protecting groups. By protecting the hydroxyl groups, well-defined polymers with tunable hydrophilicity and thermoresponsive behavior in water were obtained.
Article
Polymer Science
Kaiqi Li, Xiliang Liu, Long Chen, Zuochun Xiong, Chengdong Xiong, Dongliang Chen
Summary: Amino-functionalized polymer with enhanced hydrophilicity and antibacterial effect was synthesized by UV irradiation to remove the protecting group. Structures were confirmed by H-1 nuclear magnetic resonance (NMR) and C-13 NMR analysis. The pendant amino groups played a role in both increasing hydrophilicity and imparting positive charge for antibacterial effect.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2022)
Review
Chemistry, Multidisciplinary
Nery M. Aguilar, Jose Manuel Perez-Aguilar, Valeria J. Gonzalez-Coronel, Jesus Guillermo Soriano Moro, Brenda L. Sanchez-Gaytan
Summary: The integration of polymers in the synthesis and stabilization of inorganic nanostructures helps generate nanocomposites with outstanding capabilities. This control over nanomaterials can give them novel properties and expand the capabilities of hybrid materials.
Article
Chemistry, Physical
Zi-Gang Lu, Wenbin Chen, David Lee Phillips, Ming-De Li
Summary: In this study, blebbistatin derivatives with various electronic characteristic leaving groups were synthesized and studied to unveil the photocleavage mechanism(s) and the tunable effect of the leaving groups. The results provide a structure-property relationship that allows for rational selection of protected groups in molecules for specific applications.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Robert E. Ducker, Oscar Siles Bruegge, Anthony J. H. M. Meijer, Graham J. Leggett
Summary: We demonstrate the mechanochemical regulation of a photochemical reaction using an atomic force microscope (AFM) probe to remove photocleavable nitrophenyl protecting groups from alkylsilane films. This process enables nanoscale differentiation of chemical reactivity with high spatial resolution. The study also shows that functionalization of nanolines with nitrilo triacetic acid allows for site-specific immobilization of histidine-tagged green fluorescent protein.
Article
Chemistry, Multidisciplinary
Kerstin Halama, Andreas Schaffer, Bernhard Rieger
Summary: Polyvinylphosphonates are explored for biomedical applications due to their tunable lower critical solution temperature, high biocompatibility, and versatility for post-synthetic modifications. Polymer-analogous transformations were carried out with statistical polyvinylphosphonates containing diethyl vinylphosphonate and diallyl vinylphosphonate, leading to the successful introduction of reactive moieties and subsequent formation of complex polymer conjugates through various reactions. Characterization using NMR, FTIR, UV/Vis spectroscopy, elemental analysis, and gel permeation chromatography confirmed the structural changes and success of the modification approaches.
Article
Biochemistry & Molecular Biology
Alvaro Leonel Robles Grana, Hortensia Maldonado-Textle, Jose Roman Torres-Lubian, Claude St Thomas, Ramon Diaz de Leon, Jose Luis Olivares-Romero, Luis Valencia, Francisco Javier Enriquez-Medrano
Summary: This study demonstrates the efficient control of polymerization of methacrylic monomers using a symmetrical trithiocarbonate chain transfer agent in the RAFT process. However, an atypical behavior is observed in the polymerization of MMA, where high initiator/CTA molar ratios are required to achieve predictable molecular weights without affecting dispersity.
Article
Chemistry, Multidisciplinary
Adriana Popa, Laura Cocheci, Lavinia Lupa, Aniela Pop, Aurelia Visa
Summary: This study presents the application of novel compounds of beta-phosphonate-type glycine pendant groups grafted on S-DVB copolymer for the treatment of water contaminated with organic pollutants. The materials achieved high photocatalysis efficiency of 98.6% in removing Congo red dye.
APPLIED SCIENCES-BASEL
(2023)
Review
Biochemistry & Molecular Biology
Pengfei Wang, Chaeeun Lim
Summary: This paper focuses on the utilization of the excited state meta effect (ESME) in the development of photolabile protecting groups (PPGs). It discusses structurally simple ESME-based PPGs for releasing various functional groups and provides examples that demonstrate their advantages. It also describes the applications of these PPGs in synthesis, release of biologically important molecules, materials science, and biomedical engineering.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Dan Zhao, Dong Li, Fenli Quan, Yuhao Zhou, Zhen Zhang, Xuesi Chen, Chaoliang He
Summary: Thermoreversible hydrogels composed of PEG/P(EEO(2)LG) block copolymers exhibit rapid gel-to-sol transition rates within seconds, making them suitable for biomedical applications. These innovative hydrogels also show better biocompatibility and biodegradability compared to traditional hydrogels.
Article
Polymer Science
Arjita Kulshreshtha, Ryan C. Hayward, Arthi Jayaraman
Summary: This study investigates the effects of the distribution of hydrogen bonding chemical groups in polymer blends on the morphology of the blend, finding that the strength of hydrogen bonding and the arrangement of groups can influence the blend morphology and microphase separation phenomena.
Article
Materials Science, Biomaterials
Tobias Alexander Bauer, Jonas Eckrich, Nadine Wiesmann, Felix Kuczelinis, Wen Sun, Xiaolong Zeng, Benjamin Weber, Si Wu, Nicolas Hubert Bings, Sebastian Strieth, Matthias Barz
Summary: The study demonstrates the combination of light-sensitive polypyridyl-ruthenium(ii) complexes with polypept(o)ides to form photocleavable core cross-linked polymeric micelles, which have the potential for drug release and enhanced stability. Analysis shows increased cytotoxicity with micellar delivery of [Ru(bpy)(2)(H2O)(2)](2+) and mostly irradiation damage for [Ru(biq)(2)(H2O)(2)](2+), pointing towards the future development of quick-release complexes with stable circulation.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Engineering, Environmental
Hao Zhang, Nan Tang, Xia Yu, Zhongkai Guo, Zhen Liu, Xiaoming Sun, Min-Hui Li, Jun Hu
Summary: This study presents a high-performance and multi-functional hydrogel prepared by simple and green methods, with anti-freezing and anti-drying properties. Additionally, a gradient silver nanoparticles layer can be constructed in situ on the hydrogel surface to enhance sensing performance, making it suitable for assembling sensors to detect human motion.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Baoyan Zhang, Xia Yu, Jiawei Li, Kailun Wei, Liang Gao, Jun Hu
Summary: In this work, a four-armed biobased AIE fluorescent gelator (TPE-4GL) was designed and synthesized by linking four glycyrrhizic acids to a tetraphenylethene (TPE) core. TPE-4GL exhibited stable gels in DMSO/water and 1,2-propanediol/water, with flower-like microstructures and regular nanospheres. The gelator demonstrated the aggregation-induced emission (AIE) behavior, although the specific process differed in DMSO/water and 1,2-propanediol/water.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Hao Zhang, Ning Tang, Xia Yu, Min-Hui Li, Jun Hu
Summary: This paper presents a strategy to prepare strong and tough physical eutectogels using a solvent-replacement approach. By replacing water with deep eutectic solvents, the interactions between polymer chains can be restrengthened, resulting in eutectogels with high strength, toughness, and tear resistance, as well as excellent stretchability, repairability, and adhesive performance.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Environmental
Kailun Wei, Kefei Zhao, Yuxia Gao, Hao Zhang, Xia Yu, Min-Hui Li, Jun Hu
Summary: In this study, a near-infrared responsive poly-sulfide carrier (SOCT) was prepared using industrial waste sulfur, bio-based soybean oil, and agricultural waste biochar. The carrier exhibited good photothermal property and stable release behavior, allowing for controlled release of the pesticide. It also showed excellent fungicidal activities and high biosafety for plants and fish. The carrier material can be completely degraded in specific conditions, making it sustainable and multi-functional. This research provides an effective approach for developing pesticide formulations with improved performance.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Polymer Science
Hao Zhang, Jianqiao Wu, Junbo Guo, Jun Hu
Summary: With the concept of sustainable development becoming increasingly prominent, the world is shifting from a fossil fuel-driven energy economy to one that relies more on renewable and sustainable materials. Terpenoids, a category of natural products found in plants, microorganisms, and marine animals, have numerous modification sites and diverse functions. They can be used to create sustainable materials with simplified synthesis processes, distinctive stereoscopic configurations, superior bioactivity, and biocompatibility, enabling greater applications in various fields. This review focuses on the recent advances in the preparation, properties, and development directions of sustainable and multifunctional materials derived from terpenoids, including terpenoid-derived thermoplastics, cross-linked polymers, and supramolecular materials. It aims to raise awareness of natural terpenoids, promote their exploitation and utilization, and provide more alternatives for the advancement of sustainable functional materials.
Article
Chemistry, Multidisciplinary
Huangjie Lu, Hailong Huang, Junpu Yang, Zhaofa Zheng, Xue Dong, Lianjie Zhao, Chao Xu, Jun Hu, Hongtao Liu, Yuan Qian, Jian-Qiang Wang, Jian Lin
Summary: Developing UV radiation sensors with high sensitivity, easy operation, and rapid readout is desired in various fields. Enhancing the sensitivity of UV detection, particularly for photochromic materials, has been a challenge. In this study, a viologen derivative incorporated with a hydrogel-based UV sensor was formulated, which exhibited a reversible photoelectrochromic response and improved UV sensitivity by two orders of magnitude. The proposed strategy of constructing photoelectrochromic hybrids could potentially enhance the UV sensitivity of other photochromic materials as well.
Article
Nanoscience & Nanotechnology
Lianjie Zhao, Hao Zhang, Ning Tang, Min-Hui Li, Jun Hu
Summary: Phytic acid-assisted PANi/PVA hydrogel with self-reinforcing features is developed, showing enhanced mechanical performance. Phytic acid plays a crucial role in salinizing aniline and forming hydrogen bonds with PVA, resulting in conductive PANi and structure orientation. The hydrogel exhibits improved fracture strength, Young’s modulus, and toughness after repetitive stretching, attributed to the anisotropic structures fixed by hydrogen bonds. The PVA/PA/PANi hydrogel shows good mechanical durability and reusability, making it a reliable strain sensor.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Zhiran Zheng, Jiawei Li, Kailun Wei, Ning Tang, Min-Hui Li, Jun Hu
Summary: This study develops an integrated auxetic elastomer (IAE) that can exhibit transverse expansion while being axially stretched. By using high-modulus cross-linked poly(urethane-urea) as a skeleton and low-modulus non-cross-linked poly(urethane-urea) as a complementary-shape matrix, along with the dual dynamic interfacial healing promoted by disulfide bonds and hydrogen bonds, the resulting IAE possesses flat, void-free, and sharp soft-to-hard interface-free characteristics. Moreover, the fracture strength and elongation at the break of the IAE are significantly improved compared to those of the corrugated re-entrant skeleton alone, while maintaining the negative Poisson's ratio (NPR) within a certain strain range. Finite element analysis further confirms the advantageous mechanical and auxetic properties of this elastomer.
ADVANCED MATERIALS
(2023)
Article
Engineering, Environmental
Baoyan Zhang, Tiantian Cui, Xuewei Jiao, Yaning Ma, Liang Gao, Jun Hu
Summary: A catalyst-free covalent adaptable network with high mechanical and thermal properties is developed for carbon fiber-reinforced composites. The material possesses rapid transesterification reactions, allowing for reprocessing, repairing, and degradation. Moreover, the composite exhibits good welding ability and can be efficiently and non-destructively recycled.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Junbo Guo, Hao Zhang, Tiantian Cui, Jiawei Li, Min-Hui Li, Jun Hu
Summary: In this study, a viewable in situ programmed humidity-driven monolayer actuator was reported, which consisted of hydrophilic poly(vinyl alcohol) (PVA), polyacrylamide (PAAm), and tannic acid (TA). The inclusion of TA as a physical cross-linker allowed for precise control of modulus distribution, while also providing fluorescence in the solid state. The resulting film exhibited high optical transparency, good mechanical properties, bright fluorescence, and reversible fast humidity-response. This viewable and programmable approach will greatly aid in the design of humidity-driven actuators for various applications.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Materials Science, Multidisciplinary
Xia Yu, Jiawei Li, Hao Zhang, Min-Hui Li, Jun Hu
Summary: Using natural glycyrrhetinic acid (GA) with good self-assembly ability and hydrophilic polyethylene glycol (PEG) with thermoresponsive capacity, we synthesized amphiphilic trans-/cis-TPE-GA-PEG isomers with aggregation-induced emission (AIE) characteristics. The trans isomers formed nanospheres with typical AIE features, while the cis isomers displayed a fluorescence-enhanced property and generated nanovesicles. Both isomers underwent reversible phase transitions in tetrahydrofuran/water solution, with the cis isomers having a lower phase transition temperature compared to the trans-TPE-GA-PEG. The morphologies of the isomers transformed into helical fibers and irregular aggregates, respectively, due to the disruption of interactions between PEG chains and water molecules.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Zhongkai Guo, Xuewei Jiao, Kailun Wei, Jianqiao Wu, Jun Hu
Summary: In this study, a series of itaconic acid-based vitrimers with dual-dynamic networks were prepared by one-pot inverse vulcanization, which resolved the challenges of competitive raw materials and tedious preparation process for application of sustainable polymers. These vitrimers exhibited good solvent resistance and thermal stability, and could be physically recycled, repaired, welded, and chemically degraded at a mild temperature.
Article
Chemistry, Multidisciplinary
Ning Tang, Yujia Jiang, Kailun Wei, Zhiran Zheng, Hao Zhang, Jun Hu
Summary: A stepwise-enhanced strategy is presented to fabricate ultrarobust eutectogels. The strategy involves complementary annealing and solvent exchange processes to optimize polymer networks and enhance mechanical properties. The resultant eutectogel exhibits exceptional mechanical performance and can be programmed through photolithography.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Hao Zhang, Junbo Guo, Jun Hu, Ming Zhou
Summary: With the advancement of supramolecular chemistry, the focus is shifting towards the development of multifunctional supramolecular materials. Natural small molecules are preferred over synthetic molecules due to their lower toxicity, better biocompatibility, biodegradability, and bioactivity. Terpenoids, with their wide range of supply sources, numerous modification sites, and abundant functions, have become a promising platform for constructing supramolecular materials. Many terpenoid-based supramolecular materials have been successfully developed, playing important roles in various fields such as tissue engineering, biomedicine, food science, and flexible electronics.
SUPRAMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yuzhang Meng, Zilu Li, Chenxia Xie, Yuxia Gao, Xia Yu, Hao Zhang, Hui Li, Jun Hu
Summary: This study successfully inhibits droplet bounce on solid interfaces by synthesizing a self-assembled material, and demonstrates its feasibility in a real environment.
CELL REPORTS PHYSICAL SCIENCE
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
