4.7 Article

Internal Lewis acid assisted ureas: tunable hydrogen bond donor catalysts

Journal

CHEMICAL COMMUNICATIONS
Volume 49, Issue 39, Pages 4289-4291

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc37073e

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Funding

  1. OSU Department of Chemistry
  2. American Chemical Society Petroleum Research Foundation [52183-DNI1]

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The strategic incorporation of internal Lewis acids onto urea scaffolds gives rise to a family of tunable hydrogen bond donor catalysts. The nature of the Lewis acid and associated ligands affects the urea polarization, acidity, and activity in reactions of nitrocyclopropane carboxylates and nitrodiazoesters.

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