4.7 Article

A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 79, Pages 9927-9929

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc35235d

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Funding

  1. National Natural Science Foundation of China [21272202]
  2. Fundamental Research Funds for the Central Universities

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1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of alpha-amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH2Cl2. This methodology was utilized to synthesize 2-benzoyl quinolines.

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