4.7 Article

Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 27, Pages 3309-3311

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc18107j

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Funding

  1. National Natural Science Foundation of China [20905062, 21075100]
  2. Fundamental Research Funds for the Central Universities [XDJK2012A004]

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By using exonuclease I and biobarcode nanoparticles, we describe a novel background current reduction strategy for amplified electrochemical detection of uropathogen specific sequences at ultralow concentrations.

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