Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 65, Pages 8111-8113Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc33743f
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- CEA
- Les Laboratoires Pierre Fabre
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A novel approach for the asymmetric synthesis of the active (1S,2R)-enantiomer of the antidepressant milnacipran is reported. The two stereogenic centers borne by the cyclopropane ring were sequentially installed starting from phenylacetic acid.
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