Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 91, Pages 11256-11258Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc36176k
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Funding
- NIH [R21AT006767]
- NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES [UL1TR000062] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR COMPLEMENTARY & ALTERNATIVE MEDICINE [R21AT006767] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR RESEARCH RESOURCES [UL1RR029882] Funding Source: NIH RePORTER
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In the presence of triphenylphosphine, copper(II) chloride can catalyze an intermolecular ortho-acylation reaction of phenols with aryl aldehydes. The reaction proceeds smoothly with a wide range of starting materials, and furthermore, it can be used to synthesize xanthone derivatives in a single step in high yields.
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