Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 32, Pages 3836-3838Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc30928a
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Funding
- National Natural Science Foundation of China [21032007, 21172038]
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A palladium-catalyzed three-component reaction of bis-(2-iodoaryl)carbodiimide, isocyanide, and amine gives rise to quinazolino[3,2-a]quinazolines and related compounds in good yields. Multi-bonds are formed in one pot through nucleophilic attack, isocyanide insertion, and C-N coupling during the reaction process.
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