Direct asymmetric Mannich reaction of phthalides: facile access to chiral substituted isoquinolines and isoquinolinones

Highly enantioselective [4 + 2] annulations catalyzed by amino acid-based phosphines: Synthesis of functionalized cyclohexenes and 3-spirocyclohexene-2-oxindoles

(2012) Fangrui Zhong et al.   Chemical Science

Enantioselective Synthesis of Chromanones via a Tryptophan- Derived Bifunctional Thiourea-Catalyzed Oxa-Michael-Michael Cascade Reaction

(2011) Haifei Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Enantioselective [3+2] Annulation of Morita-Baylis-Hillman Adducts Mediated by L-Threonine-Derived Phosphines: Synthesis of 3-Spirocyclopentene-2-oxindoles having Two Contiguous Quaternary Centers

(2011) Fangrui Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Direct Asymmetric Vinylogous Aldol Reaction of Furanones with α-Ketoesters: Access to Chiral γ-Butenolides and Glycerol Derivatives

(2011) Jie Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereochemical Investigations of Isochromenones and Isobenzofuranones Isolated fromLeptosphaeriasp. KTC 727

(2011) Wilanfranco C. Tayone et al.   JOURNAL OF NATURAL PRODUCTS

Enantioselective [3 + 2] Cycloaddition of Allenes to Acrylates Catalyzed by Dipeptide-Derived Phosphines: Facile Creation of Functionalized Cyclopentenes Containing Quaternary Stereogenic Centers

(2011) Xiaoyu Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Primary Amine/CSA Ion Pair: A Powerful Catalytic System for the Asymmetric Enamine Catalysis

(2011) Chen Liu et al.   ORGANIC LETTERS

Highly Enantioselective Amination Reactions of Fluorinated Keto Esters Catalyzed by Novel Chiral Guanidines Derived from Cinchona Alkaloids

(2010) Xiao Han et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Direct Vinylogous Aldol Reaction of Furanone Derivatives Catalyzed by an Axially Chiral Guanidine Base

(2010) Hitoshi Ube et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereocontrolled Creation of All-Carbon Quaternary Stereocenters by Organocatalytic Conjugate Addition of Oxindoles to Vinyl Sulfone

(2010) Qiang Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral primary amine mediated conjugate addition of branched aldehydes to vinyl sulfone: asymmetric generation of quaternary carbon centers

(2010) Qiang Zhu et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric direct vinylogous aldol reactions of γ-crotonolactone with aromatic aldehydes

(2010) Sunil V. Pansare et al.   CHEMICAL COMMUNICATIONS

A Practical Synthesis of 1-Oxo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid Esters

(2010) Lei Tang et al.   CHINESE JOURNAL OF CHEMISTRY

Reductive Ring-Opening of Phthalan and Isochroman: Application to the Stereoselective Synthesis of Tetrahydroisoquinolines and Tetrahydrobenzazepines

(2010) Daniel García et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Morita−Baylis−Hillman Reaction of Isatins with Acrylates: Facile Creation of 3-Hydroxy-2-oxindoles

(2010) Fangrui Zhong et al.   ORGANIC LETTERS

Direct asymmetric aldol reaction of acetone with α-ketoesters catalyzed by primary–tertiary diamine organocatalysts

(2010) Zhaoqin Jiang et al.   TETRAHEDRON LETTERS

Asymmetric Mannich Reaction of Fluorinated Ketoesters with a Tryptophan-Derived Bifunctional Thiourea Catalyst

(2009) Xiao Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists

(2009) Paul S. Humphries et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Asymmetric generation of fluorine-containing quaternary carbons adjacent to tertiary stereocenters: uses of fluorinated methines as nucleophiles

(2009) Xiao Han et al.   CHEMICAL COMMUNICATIONS

Direct Asymmetric Michael Addition to Nitroalkenes: Vinylogous Nucleophilicity under Dinuclear Zinc Catalysis

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Michael Addition Mediated by Novel Cinchona Alkaloid-Derived Bifunctional Catalysts Containing Sulfonamides

(2009) Jie Luo et al.   ORGANIC LETTERS

Stereoselective synthesis of 3-substituted tetrahydroisoquinolines from phthalan and chiral N-sulfinylimines

(2009) Daniel García et al.   TETRAHEDRON LETTERS

Syntheses and structure–activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1′-cyclohexan]-4′-yl]benzimidazole NPY Y5 receptor antagonists

(2008) Yoshio Ogino et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS