4.7 Article

Colorimetric tracking of protein structural evolution based on the distance-dependent light scattering of embedded gold nanoparticles

Journal

CHEMICAL COMMUNICATIONS
Volume 48, Issue 17, Pages 2286-2288

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2cc17174k

Keywords

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Funding

  1. WCU (World Class University) through the National Research Foundation of Korea
  2. Ministry of Education, Science and Technology [R31-10013]
  3. Sogang University
  4. National Research Foundation of Korea (NRF)
  5. Korea government (MEST) [2011-0015749]
  6. 'Center for Nanostructured Materials Technology' under Ministry of Education, Science and Technology, Korea [2011K00213]
  7. National Research Foundation of Korea [2011-0015749] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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In this communication, we describe a new, simplified colorimetric method for in situ tracking of structural evolution of Cu/Zn-superoxide dismutase (SOD1) aggregates, based on changes in plasmonic coupling between gold nanoparticles (GNPs) embedded along the structural backbone of the SOD1 aggregates.

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