4.7 Article

Extraction and isolation of shikimic acid from Ginkgo biloba leaves utilizing an ionic liquid that dissolves cellulose

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 38, Pages 10560-10562

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc13306c

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Funding

  1. Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan

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Shikimic acid, the starting material in the commercial synthesis of oseltamivir phosphate (Tamiflu (R)), was efficiently extracted and isolated from Ginkgo biloba leaves utilizing the ionic liquid 1-butyl-3-methylimidazolium chloride ([bmim]Cl), which dissolves cellulose.

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